ACSL3

Gene Symbol	ACSL3
Entrez Gene	2181
Alt Symbol	ACS3, FACL3, PRO2194
Species	Human
Gene Type	protein-coding
Description	acyl-CoA synthetase long-chain family member 3
Other Description	LACS 3|fatty-acid-Coenzyme A ligase, long-chain 3|lignoceroyl-CoA synthase|long-chain acyl-CoA synthetase 3|long-chain-fatty-acid--CoA ligase 3
Swissprots	Q8IUM9 Q60I92 O95573
Accessions	BAB72139 CBF65064 CBU89935 EAW70807 EAW70808 EAW70809 O95573 AB061712 BAB72074 AF116690 AAF71110 AI378485 AK001471 BAG50918 AK023191 BAG51167 AK314621 BAG37187 BC012066 BC032144 AAH32144 BC041692 AAH41692 BF679686 BG772246 BM971377 BQ435549 BX472576 D89053 BAA37142 N44998 XR_922889 NM_004457 NP_004448 NM_203372 NP_976251
Function	Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL3 mediates hepatic lipogenesis (By similarity). Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates (By similarity). Has mainly an anabolic role in energy metabolism. Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins). {ECO:0000250, ECO:0000269|PubMed:18003621}.
Subcellular Location	Mitochondrion outer membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Peroxisome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}.
Top Pathways	Adipocytokine signaling pathway, PPAR signaling pathway, Peroxisome, Fatty acid biosynthesis, Fatty acid degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ACSL3 293T Cell Transient Overexpression Lysate(Denatured) - H00002181-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

ACSL3 293 Cell Lysate - 408401 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

ACSL3 293 Cell Lysate - 403195 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

ACSL3 Overexpression Lysate (Denatured) - H00002181-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

ACSL3 Overexpression Lysate (Native) - NBL1-07262 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

ACSL3 Overexpression Lysate (Native) - NBL1-07263 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

ACSL3 Over-expression Lysate Product - GWB-BAC607 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

ACSL3 Over-expression Lysate Product - GWB-1E65E3 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Panoply™ Human ACSL3 Knockdown Stable Cell Line - CSC-DC000170 from Creative biogene Category Cell Line Species Human

Human ACSL3 Knockout Cell Line-HeLa - CSC-RT1572 from Creative biogene Category Cell Line Species Human

ACSL3 KO Cell Lysate-HeLa - CLKO-1419 from Creative biogene Category Cell Lysate

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