ACSL3

Gene Symbol	ACSL3
Entrez Gene	2181
Alt Symbol	ACS3, FACL3, PRO2194
Species	Human
Gene Type	protein-coding
Description	acyl-CoA synthetase long-chain family member 3
Other Description	LACS 3|fatty-acid-Coenzyme A ligase, long-chain 3|lignoceroyl-CoA synthase|long-chain acyl-CoA synthetase 3|long-chain-fatty-acid--CoA ligase 3
Swissprots	Q8IUM9 Q60I92 O95573
Accessions	BAB72139 CBF65064 CBU89935 EAW70807 EAW70808 EAW70809 O95573 AB061712 BAB72074 AF116690 AAF71110 AI378485 AK001471 BAG50918 AK023191 BAG51167 AK314621 BAG37187 BC012066 BC032144 AAH32144 BC041692 AAH41692 BF679686 BG772246 BM971377 BQ435549 BX472576 D89053 BAA37142 N44998 XR_922889 NM_004457 NP_004448 NM_203372 NP_976251
Function	Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL3 mediates hepatic lipogenesis (By similarity). Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates (By similarity). Has mainly an anabolic role in energy metabolism. Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins). {ECO:0000250, ECO:0000269|PubMed:18003621}.
Subcellular Location	Mitochondrion outer membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Peroxisome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}.
Top Pathways	Adipocytokine signaling pathway, PPAR signaling pathway, Peroxisome, Fatty acid biosynthesis, Fatty acid degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ACSL3 Antibody Blocking Peptide - LS-E4348 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACSL3 Antibody Blocking Peptide - LS-E6996 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ACSL3 Protein - H00002181-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ACSL3 Protein - H00002181-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

ACSL3 Peptide - P1149 from Novus Biologicals Category Peptide Species Human

ACSL3-Antibody-C-term-Blocking-Peptide - BP16647b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ACSL3-FACL3-Antibody-N-term-Blocking-peptide - BP2535a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ACSL3 Blocking Peptide - 33R-4845 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ACSL3 - H00002181-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

ACSL3 - H00002181-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ACSL3 - H00002181-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human ACSL3, His-tagged - ACSL3-26480TH from Creative Biomart Category Protein Source E. coli

Recombinant Human Long-chain-fatty-acid--CoA ligase 3(ACSL3) - CSB-YP001192HU CSB-EP001192HU CSB-BP001192HU CSB-MP001192HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ACSL3 (transcript variant 1) - TP308032 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ACSL3 (transcript variant 2) - TP317537 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ACSL3 Recombinant Protein Antigen - NBP1-89268PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ACSL3-FACL3-Antibody-Center-Blocking-peptide - BP2535b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ACSL3 Peptide, Human - M34GP00170H from Creative Peptides Category Peptide Source Synthetic. Species Human

ACSL3 Recombinant Protein Antigen - NBP2-58817PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Long-chain-fatty-acid--CoA ligase 3, Recombinant Protein - MBS7042062 from MyBioSource Category Protein Prices $1,505.00, $2,490.00, $3,695.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Long-chain-fatty-acid--CoA ligase 3 (ACSL3), Recombinant Protein - MBS1257292 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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