PPP2R5A

Gene Symbol PPP2R5A
Entrez Gene 5525
Alt Symbol B56A, PR61A
Species Human
Gene Type protein-coding
Description protein phosphatase 2, regulatory subunit B', alpha
Other Description PP2A B subunit isoform B'-alpha|PP2A B subunit isoform B56-alpha|PP2A B subunit isoform PR61-alpha|PP2A B subunit isoform R5-alpha|PP2A, B subunit, B' alpha isoform|PP2A, B subunit, B56 alpha isoform|PP2A, B subunit, PR61 alpha isoform|PP2A, B subunit, R5 alpha isoform|PR61alpha|protein phosphatase 2, regulatory subunit B (B56), alpha isoform|protein phosphatase 2, regulatory subunit B', alpha isoform|serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, alpha isoform|serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
Swissprots B7Z7L2 B2R6D2 Q8TBI9 D3DT99 Q15172 Q5VVB2 Q2NL72
Accessions EAW93392 EAW93393 Q15172 AA425592 AK302202 BAH13648 AK312530 BAG35429 BC022474 AAH22474 BC110883 AAI10884 BM974076 BP326450 DQ892361 ABM83287 DQ895568 ABM86494 L42373 AAC37601 NM_001199756 NP_001186685 NM_006243 NP_006234
Function The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:8703017}. Nucleus {ECO:0000269|PubMed:8703017}. Chromosome, centromere {ECO:0000269|PubMed:16541025}. Note=From mitotic prophase to metaphase, localizes at the inner centromere between a pair of sister kinetochores. Decreased expression at the onset of anaphase. {ECO:0000269|PubMed:16541025}.
Tissue Specificity Widely expressed with the highest expression in heart and skeletal muscle.
Top Pathways Oocyte meiosis, mRNA surveillance pathway, Dopaminergic synapse, PI3K-Akt signaling pathway, Adrenergic signaling in cardiomyocytes

Human PPP2R5A ORF Clone(NM_006243.3) - CDCL172565 from Creative Biomart

Species Human
Accession NM_006243.3

human PPP2R5A ORF clone (NM_001199756.1) - CDCH067042 from Creative biogene

Species Human
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