Gene Symbol | HIST1H2BD |
---|---|
Entrez Gene | 3017 |
Alt Symbol | H2B.1B, H2B/b, H2BFB, HIRIP2, dJ221C16.6 |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H2bd |
Other Description | H2B histone family, member B|HIRA-interacting protein 2|histone 1, H2bd|histone H2B type 1-D|histone H2B.1 B|histone H2B.b |
Swissprots | P58876 |
Accessions | AAA63190 AAN06687 EAW55535 EAW55536 P58876 AJ223353 CAA11277 AK292712 BAF85401 BC002842 AAH02842 BC096122 AAH96122 BE245851 BM153714 XM_005249039 XP_005249096 NM_021063 NP_066407 NM_138720 NP_619790 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism |