Gene Symbol | HIST1H2BD |
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Entrez Gene | 3017 |
Alt Symbol | H2B.1B, H2B/b, H2BFB, HIRIP2, dJ221C16.6 |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H2bd |
Other Description | H2B histone family, member B|HIRA-interacting protein 2|histone 1, H2bd|histone H2B type 1-D|histone H2B.1 B|histone H2B.b |
Swissprots | P58876 |
Accessions | AAA63190 AAN06687 EAW55535 EAW55536 P58876 AJ223353 CAA11277 AK292712 BAF85401 BC002842 AAH02842 BC096122 AAH96122 BE245851 BM153714 XM_005249039 XP_005249096 NM_021063 NP_066407 NM_138720 NP_619790 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism |
Histone cluster 1 H2BD CRISPR/Cas9 KO Plasmid (h) - sc-417587 from Santa Cruz Biotechnology
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Histone cluster 1 H2BD HDR Plasmid (h) - sc-417587-HDR from Santa Cruz Biotechnology
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Histone cluster 1 H2BD Double Nickase Plasmid (h) - sc-417587-NIC from Santa Cruz Biotechnology
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Histone cluster 1 H2BD Double Nickase Plasmid (h2) - sc-417587-NIC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BD CRISPR Activation Plasmid (h) - sc-417587-ACT from Santa Cruz Biotechnology
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Histone cluster 1 H2BD CRISPR Activation Plasmid (h2) - sc-417587-ACT-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BD Lentiviral Activation Particles (h) - sc-417587-LAC from Santa Cruz Biotechnology
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Histone cluster 1 H2BD Lentiviral Activation Particles (h2) - sc-417587-LAC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BD siRNA (h) - sc-105474 from Santa Cruz Biotechnology
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Histone cluster 1 H2BD shRNA Plasmid (h) - sc-105474-SH from Santa Cruz Biotechnology
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Histone cluster 1 H2BD shRNA (h) Lentiviral Particles - sc-105474-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU110151 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10071 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10071 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02946 from Sigma-Aldrich
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HIST1H2BD siRNA (Human) - CRH2050 from Cohesion Biosciences
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HIST1H2BD siRNA (Human) - CRH2051 from Cohesion Biosciences
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HIST1H2BD - MBS8214102 from MyBioSource
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shRNA set against Human HIST1H2BD (NM_021063.3) - SHH312577 from Creative biogene
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HIST1H2BD shRNA Plasmid (Human) - CHH2050 from Cohesion Biosciences
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HIST1H2BD shRNA Plasmid (Human) - CHH2051 from Cohesion Biosciences
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HIST1H2BD miRNA 3'UTR clone - MiUTR3H-05327 from Creative biogene
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HIST1H2BD miRNA 3'UTR clone - MiUTR3H-05328 from Creative biogene
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