Slit2

Gene Symbol	Slit2
Entrez Gene	360272
Alt Symbol	-
Species	Rat
Gene Type	protein-coding
Description	slit homolog 2 (Drosophila)
Other Description	slit homolog 2 protein|slit-2
Swissprots	Q9WVC1
Accessions	EDL99919 Q9WVC1 XM_008770210 XP_008768432 NM_022632 NP_072154
Function	Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth- stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post- crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for
Subcellular Location	Secreted {ECO:0000250}.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Slit Homolog 2 (Slit2), Rat, ELISA Kit - SEA672Ra from ARP American Research Products Category ELISA Kit Prices $704.00 Sizes 96 t Sensitivity 0.053ng/mL Range 0.156-10ng/mL

Slit homolog 2 protein, Slit2, Rat, ELISA Kit - E0672r from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Rat Slit2 ELISA Kit - RS0119 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Rat SLIT2(Slit Homolog 2) ELISA Kit - E-EL-R0886 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Rat Slit Homolog 2 ELISA - E02S0112 from BlueGene Biotech Category ELISA Kit Sensitivity 0.1 ng/ml

Rat SLIT2(Slit Homolog 2) ELISA Kit - E-EL-R0886 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.1 ng/mL Range 0.16~10 ng/mL

Slit Homolog 2 (Slit2), Rat, ELISA Kit - DL-Slit2-Ra from ARP American Research Products Category ELISA Kit Prices $715.00 Sizes 96 t Range 0.156-10 ng/mL

Rat Slit2 ELISA Kit - abx570585 from Abbexa Category ELISA Kit Sensitivity 0.053 ng/ml Range 0.156 ng/ml - 10 ng/ml

SLIT2 - EKR2680 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156--10ng/ml

Rat Slit2 ELISA Kit - E098052 from Biobool Category ELISA Kit

Slit2 ELISA Kit (Rat) (OKDD00641) - OKDD00641 from Aviva Systems Biology Category ELISA Kit Prices $570.00 Sizes 96 wells Sensitivity <0.053 ng/mL Range 0.156-10 ng/mL

Rat Slit2 ELISA Kit - ERS0119 from ABclonal Category ELISA Kit Prices $495.00 Sizes 96 t

SLIT2 ELISA Kit (Rat) (OKCD02863) - OKCD02863 from Aviva Systems Biology Category ELISA Kit Prices $535.00 Sizes 5 ng Sensitivity 30 pg/mL Range 78.12-5,000 pg/mL

Rat Slit homolog 2 protein (SLIT2) ELISA Kit - AE18235RA from ARP American Research Products Category ELISA Kit Prices $610.00 Sizes 96 t Sensitivity 30 pg/mL Range 78.12-5000 pg/mL

Slit Homolog 2 (Slit2), ELISA Kit - MBS453695 from MyBioSource Category ELISA Kit Prices $410.00, $540.00, $2,380.00, $4,620.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.053ng/mL Range 0.156-10ng/mL

Slit homolog 2 protein, ELISA Kit - MBS2882758 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

SLIT2 ELISA Kit (Rat) (OKEH07160) - OKEH07160 from Aviva Systems Biology Category ELISA Kit Sensitivity 0.312 ng/mL Range 0.313 - 20 ng/mL

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