AR

Gene Symbol	AR
Entrez Gene	367
Alt Symbol	AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
Species	Human
Gene Type	protein-coding
Description	androgen receptor
Other Description	androgen nuclear receptor variant 2|dihydrotestosterone receptor|nuclear receptor subfamily 3 group C member 4
Swissprots	A2RUN2 Q9UD95 P10275 B1AKD7
Accessions	AAA51772 AAA51778 AAA51886 AAB21256 AAB21257 AAB60346 AAF04001 CAA55328 CCV20035 EAX05380 P10275 AF162704 AAD45921 AF321914 AAK09423 AF321915 AAK09424 AF321916 AAK09425 AF321917 AAK09426 AI352339 BC132975 AAI32976 FJ235916 ACN39559 FJ235917 ACN39560 FJ235918 ACN39561 FJ235919 ACN39562 FJ235920 ACN39563 GU208210 ACZ81436 HM055487 ADK91081 HQ692823 ADZ17334 KF720403 AHC70786 KF720404 AHC70787 KF720405 AHC70788 KJ534771 AHW56411 L29496 AAA51770 M20132 AAA51729 M20260 AAA51774 M21748 AAA51771 M23263 AAA51775 M34233 AAA51780 M73069 AAA51735 NM_000044 NP_000035 NM_001011645 NP_001011645
Function	Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. {ECO:0000269|PubMed:14664718, ECO:0000269|PubMed:15563469, ECO:0000269|PubMed:17591767, ECO:0000269|PubMed:17911242, ECO:0000269|PubMed:18084323, ECO:0000269|PubMed:19345326, ECO:0000269|PubMed:20980437}.
Subcellular Location	Nucleus. Cytoplasm. Note=Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of GNB2L1.
Tissue Specificity	Isoform 2 is mainly expressed in heart and skeletal muscle. {ECO:0000269|PubMed:15634333}.
Top Pathways	Prostate cancer, Oocyte meiosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human AR ORF clone(NM_000044.3) - CDCH016459 from Creative Biomart Species Human Accession NM_000044.3

Human Androgen receptor/NR3C4 Gene ORF cDNA clone in cloning vector - HG13116-G from Sino Biological Species Human

Human Androgen receptor/NR3C4 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13116-CM from Sino Biological Species Human

Human Androgen receptor/NR3C4 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13116-ACG from Sino Biological Species Human

Human Androgen receptor/NR3C4 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13116-ACR from Sino Biological Species Human

Human Androgen receptor/NR3C4 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG13116-ANR from Sino Biological Species Human

Human Androgen receptor/NR3C4 Gene ORF cDNA clone expression plasmid, C-His tag - HG13116-CH from Sino Biological Species Human

Human Androgen receptor/NR3C4 Gene ORF cDNA clone expression plasmid - HG13116-UT from Sino Biological Species Human

Human AR Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG13116-G-N from Sino Biological Species Human Accession NM_001011645.1

Human Androgen receptor/NR3C4 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13116-CY from Sino Biological Species Human

Human Androgen receptor/NR3C4 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13116-NF from Sino Biological Species Human

Human Androgen receptor/NR3C4 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13116-NY from Sino Biological Species Human

Human Androgen receptor/NR3C4 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG13116-ANG from Sino Biological Species Human

Human Androgen receptor/NR3C4 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13116-NM from Sino Biological Species Human

Human Androgen receptor/NR3C4 Gene ORF cDNA clone expression plasmid, N-His tag - HG13116-NH from Sino Biological Species Human

Human Androgen receptor/NR3C4 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13116-CF from Sino Biological Species Human

Human Androgen R/NR3C4 (NP_000035) VersaClone cDNA - RDC1285 from R&D Systems Prices $499.00 Sizes 10 µg Species Human

Human AR ORF clone(NM_000044.3) - CDCH016459 from Creative biogene Species Human

Human Androgen Receptor Gene - orb93555 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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