AR

Gene Symbol	AR
Entrez Gene	367
Alt Symbol	AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
Species	Human
Gene Type	protein-coding
Description	androgen receptor
Other Description	androgen nuclear receptor variant 2|dihydrotestosterone receptor|nuclear receptor subfamily 3 group C member 4
Swissprots	A2RUN2 Q9UD95 P10275 B1AKD7
Accessions	AAA51772 AAA51778 AAA51886 AAB21256 AAB21257 AAB60346 AAF04001 CAA55328 CCV20035 EAX05380 P10275 AF162704 AAD45921 AF321914 AAK09423 AF321915 AAK09424 AF321916 AAK09425 AF321917 AAK09426 AI352339 BC132975 AAI32976 FJ235916 ACN39559 FJ235917 ACN39560 FJ235918 ACN39561 FJ235919 ACN39562 FJ235920 ACN39563 GU208210 ACZ81436 HM055487 ADK91081 HQ692823 ADZ17334 KF720403 AHC70786 KF720404 AHC70787 KF720405 AHC70788 KJ534771 AHW56411 L29496 AAA51770 M20132 AAA51729 M20260 AAA51774 M21748 AAA51771 M23263 AAA51775 M34233 AAA51780 M73069 AAA51735 NM_000044 NP_000035 NM_001011645 NP_001011645
Function	Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. {ECO:0000269|PubMed:14664718, ECO:0000269|PubMed:15563469, ECO:0000269|PubMed:17591767, ECO:0000269|PubMed:17911242, ECO:0000269|PubMed:18084323, ECO:0000269|PubMed:19345326, ECO:0000269|PubMed:20980437}.
Subcellular Location	Nucleus. Cytoplasm. Note=Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of GNB2L1.
Tissue Specificity	Isoform 2 is mainly expressed in heart and skeletal muscle. {ECO:0000269|PubMed:15634333}.
Top Pathways	Prostate cancer, Oocyte meiosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Androgen Receptor peptide - ab45603 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Androgen Receptor peptide - ab174742 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Androgen Receptor peptide - ab4903 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Androgen Receptor peptide - ab191380 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human Androgen Receptor full length protein - ab82609 from Abcam Category Protein Prices $340.00 Sizes 5 µg Source Baculovirus Species Human

Human Androgen Receptor peptide - ab13839 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human Androgen Receptor protein fragment - ab82124 from Abcam Category Protein Prices $297.00 Sizes 10 µg Source Baculovirus Species Human

Human Androgen Receptor protein fragment - ab157902 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

AR-Antibody-Center-Blocking-peptide - BP13058c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

AR-Antibody-Center-Blocking-peptide - BP13255c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Androgen Receptor blocking peptide - GTX19066-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Pig, Rat, Bovine

Recombinant human Androgen receptor (OPCA00619) - OPCA00619 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human AR DHTR protein - orb245266 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Androgen Receptor (phospho-Ser650) Blocking Peptide - abx064293 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

Androgen Receptor (phospho-Tyr363) Blocking Peptide - abx062265 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

Human Androgen Receptor Protein - abx065299 from Abbexa Category Protein Source E.coli Species Human

Androgen Receptor Peptide - AC21-0579-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Androgen receptor - H00000367-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Androgen receptor - H00000367-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Androgen receptor Control Peptide - SP5177CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

Recombinant Human Androgen Receptor - RB-14-0003P-10 from RayBiotech Category Protein Prices $110.00 Sizes 10 µg Source Escherichia coli (E.coli) Species Human

Recombinant Human Androgen Receptor - RB-14-0003P-100 from RayBiotech Category Protein Prices $336.00 Sizes 100 µg Source Escherichia coli Species Human

Recombinant Human Androgen Receptor - RB-14-0003P-50 from RayBiotech Category Protein Prices $224.00 Sizes 50 µg Source Escherichia coli Species Human

Recombinant Human Androgen receptor - RB-14-0003P-WBC from RayBiotech Category Protein Source Escherichia coli (E.coli) Species Human

Androgen Receptor (AR), Human - 20-7595 from ARP American Research Products Category Protein Prices $485.00 Sizes 50 µg Source E.coli Species Human

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