| Gene Symbol |
Pafah2
|
| Entrez Gene |
313611
|
| Alt Symbol |
-
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
platelet-activating factor acetylhydrolase 2
|
| Other Description |
SD-PLA2|platelet-activating factor acetylhydrolase 2 40kDa|platelet-activating factor acetylhydrolase 2, 40kDa|platelet-activating factor acetylhydrolase 2, cytoplasmic|serine-dependent phospholipase A2
|
| Swissprots |
Q80Z89 P83006
|
| Accessions |
EDL80720 EDL80721 P83006 AY225592 AAO62314 XM_006239127 XP_006239189 XM_008764144 XP_008762366 NM_177932 NP_808793
|
| Function |
Catalyzes transacetylation of the acetyl group from platelet-activating factor (PAF) to lysoplasmalogen and to sphingosine, producing plasmalogen analogs of PAF and N- acetylsphingosine (C2-ceramide) respectively. Also acts as a PAF- acetylhydrolase in the absence of lipid acceptor molecules. {ECO:0000269|PubMed:10085103}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}.
|
| Top Pathways |
Ether lipid metabolism
|