Gene Symbol | Pafah2 |
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Entrez Gene | 313611 |
Alt Symbol | - |
Species | Rat |
Gene Type | protein-coding |
Description | platelet-activating factor acetylhydrolase 2 |
Other Description | SD-PLA2|platelet-activating factor acetylhydrolase 2 40kDa|platelet-activating factor acetylhydrolase 2, 40kDa|platelet-activating factor acetylhydrolase 2, cytoplasmic|serine-dependent phospholipase A2 |
Swissprots | Q80Z89 P83006 |
Accessions | EDL80720 EDL80721 P83006 AY225592 AAO62314 XM_006239127 XP_006239189 XM_008764144 XP_008762366 NM_177932 NP_808793 |
Function | Catalyzes transacetylation of the acetyl group from platelet-activating factor (PAF) to lysoplasmalogen and to sphingosine, producing plasmalogen analogs of PAF and N- acetylsphingosine (C2-ceramide) respectively. Also acts as a PAF- acetylhydrolase in the absence of lipid acceptor molecules. {ECO:0000269|PubMed:10085103}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Top Pathways | Ether lipid metabolism |
CompoZr® Knockout ZFN Kit - CKOZFN59680 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND59680 from Sigma-Aldrich
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PAFAH2 siRNA (Rat) - CRR5432 from Cohesion Biosciences
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shRNA set against Rat PAFAH2 (NM_177932.2) - SHH370044 from Creative biogene
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shRNA set against Rat Pafah2(NM_177932.2) - SHR078204 from Creative biogene
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PAFAH2 shRNA Plasmid (Rat) - CHR5432 from Cohesion Biosciences
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PAFAH2 miRNA 3'UTR clone - MiUTR1R-05603 from Creative biogene
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