Igf2r

Gene Symbol Igf2r
Entrez Gene 16004
Alt Symbol AI661837, CD222, CI-MPR, M6P/IGF2R, Mpr300
Species Mouse
Gene Type protein-coding
Description insulin-like growth factor 2 receptor
Other Description 300 kDa mannose 6-phosphate receptor|CI Man-6-P receptor|IGF-II receptor|IGF-II/CI-MPR|M6P/IGF2 receptor|M6PR|MPR 300|cation-independent MPR|cation-independent mannose 6-phosphate receptor|cation-independent mannose-6-phosphate receptor|insulin-like growth factor II receptor|mannose-6-phosphate receptor, cation independent
Swissprots Q61822 Q07113 Q6LED1
Accessions AAA37921 AAA37922 AAA39320 AAA39483 AAA98844 AAM22159 EDL02049 EDL02050 EDL02051 Q07113 AK053045 BAC35249 AK088699 BAC40512 AY644391 AAT46419 BB865604 BC031190 AAH31190 BC043457 AAH43457 BC055018 AAH55018 BC115601 BC150817 AAI50818 BC171973 AAI71973 BP757292 BQ900123 CA324933 CD545656 CF167933 CK639250 CN461279 CN530622 FJ425888 FJ425889 L19500 AAA16037 U04710 AAA19568 X60389 CAA42940 NM_010515 NP_034645
Function Acts as a positive regulator of T-cell coactivation, by binding DPP4 (By similarity). Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. {ECO:0000250}.
Subcellular Location Lysosome membrane; Single-pass type I membrane protein.
Top Pathways Lysosome

IGF-IIR CRISPR/Cas9 KO Plasmid (m) - sc-421059 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IGF-IIR HDR Plasmid (m) - sc-421059-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IGF-IIR Double Nickase Plasmid (m) - sc-421059-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IGF-IIR Double Nickase Plasmid (m2) - sc-421059-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IGF-IIR CRISPR Activation Plasmid (m) - sc-421059-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IGF-IIR CRISPR Activation Plasmid (m2) - sc-421059-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IGF-IIR Lentiviral Activation Particles (m) - sc-421059-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IGF-IIR Lentiviral Activation Particles (m2) - sc-421059-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IGF-IIR siRNA (m) - sc-37117 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

IGF-IIR shRNA Plasmid (m) - sc-37117-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

IGF-IIR shRNA (m) Lentiviral Particles - sc-37117-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU065031 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN33687 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33687 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

IGF2R siRNA (Mouse) - CRM2014 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

IGF2R - MBS8214144 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse IGF2R (NM_010515.2) - SHH317509 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Igf2r(NM_010515.2) - SHL168276 from Creative biogene

Category siRNA
Species Reactivities Mouse

IGF2R shRNA Plasmid (Mouse) - CHM2014 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
Search more