| Gene Symbol |
TYK2
|
| Entrez Gene |
7297
|
| Alt Symbol |
IMD35, JTK1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tyrosine kinase 2
|
| Other Description |
non-receptor tyrosine-protein kinase TYK2
|
| Swissprots |
Q6QB10 Q96CH0 P29597
|
| Accessions |
AAS37680 EAW84099 EAW84100 P29597 AK222672 BAD96392 AK303627 BAG64635 AK308360 AK308379 BC014243 AAH14243 CR995139 DA864169 DQ892692 ABM83618 DQ895955 ABM86881 X54637 CAA38449 XM_011528245 XP_011526547 XM_011528246 XP_011526548 XM_011528247 XP_011526549 XM_011528248 XP_011526550 XM_011528249 XP_011526551 XM_011528250 XP_011526552 XM_011528251 XP_011526553 XM_011528252 XP_011526554 NM_003331 NP_003322
|
| Function |
Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain. {ECO:0000269|PubMed:7526154}.
|
| Tissue Specificity |
Observed in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines. {ECO:0000269|PubMed:2156206}.
|
| Top Pathways |
Jak-STAT signaling pathway, Toxoplasmosis, Hepatitis C, Osteoclast differentiation, Measles
|