CRTAM

Gene Symbol CRTAM
Entrez Gene 56253
Alt Symbol CD355
Species Human
Gene Type protein-coding
Description cytotoxic and regulatory T cell molecule
Other Description class I MHC restricted T cell associated molecule|class-I MHC-restricted T cell associated molecule|class-I MHC-restricted T-cell-associated molecule|cytotoxic and regulatory T-cell molecule
Swissprots Q6IRX2 O95727 Q59EI1
Accessions CCF77045 EAW67532 O95727 AB209830 BAD93067 AF001622 AAC80267 AK293470 BAG56963 AK313578 BAG36349 BC070266 AAH70266 BX118379 CA309993 CK004240 DC305734 HQ447587 ADQ32073 XM_011542900 XP_011541202 NM_001304782 NP_001291711 NM_019604 NP_062550
Function Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. {ECO:0000250|UniProtKB:Q149L7, ECO:0000269|PubMed:15811952}.
Subcellular Location Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}.
Tissue Specificity In the immune system, expression is restricted to activated class-I MHC-restricted cells, including NKT and CD8 cells. Strongly expressed in spleen, thymus, small intestine, peripheral blood leukocyte, and in Purkinje neurons in cerebellum. Expressed at much lower levels in testis, ovary, colon, lung and lymphoid tissues. {ECO:0000269|PubMed:10811014, ECO:0000269|PubMed:15811952, ECO:0000269|PubMed:16300832}.

CRTAM (K-19) - sc-46881 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CRTAM (K-19): sc-46881. Western blot analysis of CRTAM expression in mouse spleen tissue extract.

CRTAM (C-13) - sc-46879 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CRTAM (C-13): sc-46879. Western blot analysis of mouse recombinant CRTAM fusion protein.

CRTAM (M-56) - sc-99202 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

CRTAM (N-14) - sc-46883 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CRTAM (N-14): sc-46883. Western blot analysis of CRTAM expression in Jurkat (A) and HEK293 (B) whole cell lysates.

CRTAM (N-12) - sc-46882 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CRTAM (H-300) - sc-99228 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-CRTAM antibody - ab188077 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CRTAM antibody (ab188077) at 1/250 dilutionLane 1 : Human cell line RT-4 lysateLane 2 : Human cell line U-251MG sp lysateSecondaryHRP-conjugated swine anti-rabbit immunoglobulin at 1/3000 dilutiondeveloped using the ECL technique

Anti-CRTAM antibody - ab69690 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-CRTAM antibody (ab69690) at 1/500 dilutionLane 1 : CRTAM transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-CRTAM antibody [EPR15292] - ab183708 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15292
All lanes : Anti-CRTAM antibody [EPR15292] (ab183708) at 1/10000 dilutionLane 1 : Human spleen lysateLane 2 : Human thymus lysateLane 3 : Human cerebellum lysateLane 4 : Jurkat lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-CRTAM antibody [MM0204-21A9] - ab89171 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0204-21A9

Anti-CRTAM Antibody - LS-C307100 from LifeSpan Bioscience

Host Mouse
Clonality Polyclonal

Anti-CRTAM Antibody (aa216-265) - LS-C187172 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CRTAM antibody Western Blot of ACHN. Antibody dilution: 1 ug/ml.

CRTAM Antibody [Unconjugated] - AF1695 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Western blot shows lysates of human CD8+ T cells. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human CRTAM Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1695) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for CRTAM at approximately 85 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

CRTAM Antibody - NBP2-31019 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CRTAM Antibody [NBP2-31019] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp

CRTAM Antibody - H00056253-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: CRTAM Antibody [H00056253-B01] - analysis of CRTAM expression in transfected 293T cell line by CRTAM MaxPab polyclonal antibody (B01). Lane 1: CRTAM transfected lysate (44.70 KDa). Lane 2: Non-transfected lysate.

CRTAM Antibody - H00056253-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: CRTAM Antibody [H00056253-B01P] - Analysis of CRTAM expression in transfected 293T cell line by CRTAM polyclonal antibody. Lane 1: CRTAM transfected lysate(43.23 KDa). Lane 2: Non-transfected lysate.

CRTAM Antibody (MM0204-21A9) - NBP2-12208 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0204-21A9

CRTAM Antibody (210213) [Phycoerythrin] - FAB16951P from Novus Biologicals

Prices $309.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 210213
Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with PMA and Calcium Ionomycin for 24 hours were stained with Mouse Anti-Human CRTAM PE-conjugated Monoclonal Antibody (Catalog # FAB16951P) and Mouse Anti-Human CD8a APC-conjugated Monoclonal Antibody (Catalog # FAB1509A). Quadrant markers were set based on control antibody staining (Catalog # IC0041P). View our protocol for Staining Membrane-associated Proteins.

CRTAM Antibody (210213) [Allophycocyanin] - FAB16951A from Novus Biologicals

Prices $349.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 210213
Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with PMA and Calcium Ionomycin for 24 hours were stained with Mouse Anti-Human CRTAM APC-conjugated Monoclonal Antibody (Catalog # FAB16951A) and Mouse Anti-Human CD8a PE-conjugated Monoclonal Antibody (Catalog # FAB1509P). Quadrant markers were set based on control antibody staining (Catalog # IC0041A). View our protocol for Staining Membrane-associated Proteins.

CRTAM Antibody [Biotin] - BAF1695 from Novus Biologicals

Prices $420.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

CRTAM Antibody (MM0204-21A9) [DyLight 350] - NBP2-12208UV from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone MM0204-21A9

CRTAM Antibody (MM0204-21A9) [DyLight 405] - NBP2-12208V from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone MM0204-21A9

CRTAM Antibody (MM0204-21A9) [PE] - NBP2-12208PE from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone MM0204-21A9

CRTAM Antibody (MM0204-21A9) [7C] - NBP2-12208V2 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone MM0204-21A9

CRTAM Antibody (MM0204-21A9) [PerCP] - NBP2-12208PCP from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone MM0204-21A9
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