CYP51A1

Gene Symbol CYP51A1
Entrez Gene 1595
Alt Symbol CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1
Species Human
Gene Type protein-coding
Description cytochrome P450, family 51, subfamily A, polypeptide 1
Other Description CYPLI|cytochrome P450 51A1|cytochrome P450, 51 (lanosterol 14-alpha-demethylase)|cytochrome P450-14DM|cytochrome P45014DM|cytochrome P450LI|lanosterol 14-alpha demethylase|lanosterol 14-alpha-demethylase|sterol 14-alpha demethylase
Swissprots Q99868 B4DJ55 O00772 B2RAI4 Q16850 Q8N1A8 A4D1F8 O00770 Q16784
Accessions AAB46356 AAC50951 EAL24154 EAW76858 EAW76859 Q16850 AK295932 BAG58717 AK314205 BAG36881 BC018429 AAH18429 BC032322 AAH32322 D55653 BAA09512 DA349400 DC376300 DQ891311 ABM82237 DQ894495 ABM85421 U23942 AAB39951 NM_000786 NP_000777 NM_001146152 NP_001139624
Function Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. {ECO:0000269|PubMed:20149798}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305}. Microsome membrane {ECO:0000305}.
Tissue Specificity Ubiquitously expressed with highest levels in testis, ovary, adrenal, prostate, liver, kidney and lung. {ECO:0000269|PubMed:8619637}.
Top Pathways Steroid biosynthesis

CYP51A1 CRISPR/Cas9 KO Plasmid (h) - sc-410753 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP51A1 HDR Plasmid (h) - sc-410753-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP51A1 Double Nickase Plasmid (h) - sc-410753-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP51A1 Double Nickase Plasmid (h2) - sc-410753-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP51A1 CRISPR Activation Plasmid (h) - sc-410753-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP51A1 CRISPR Activation Plasmid (h2) - sc-410753-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP51A1 Lentiviral Activation Particles (h) - sc-410753-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP51A1 Lentiviral Activation Particles (h2) - sc-410753-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP51A1 siRNA (h) - sc-89432 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP51A1 shRNA Plasmid (h) - sc-89432-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP51A1 shRNA (h) Lentiviral Particles - sc-89432-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP51A1 RNAi - H00001595-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU103691 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU105301 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1811 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1811 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09696 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09696

CYP51A1 siRNA (Human) - CRH1122 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CYP51A1 - MBS827637 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Cyp51 (NM_000786.3) - SHH273769 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CYP51A1(NM_000786.3) - SHG217927 from Creative biogene

Category siRNA
Species Reactivities Human

CYP51A1 shRNA Plasmid (Human) - CHH1122 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CYP51A1 miRNA 3'UTR clone - MiUTR1H-02644 from Creative biogene

Species Reactivities Human

CYP51A1 miRNA 3'UTR clone - MiUTR3H-04274 from Creative biogene

Species Reactivities Human
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