MSN

Gene Symbol	MSN
Entrez Gene	4478
Alt Symbol	HEL70
Species	Human
Gene Type	protein-coding
Description	moesin
Other Description	epididymis luminal protein 70|membrane-organizing extension spike protein
Swissprots	P26038
Accessions	CAB46379 EAX05398 EAX05399 P26038 AK297165 BAH12513 AK308486 AK309354 AK309986 BC001112 AAH01112 BC011827 AAH11827 BC017293 AAH17293 CN386296 DQ892653 ABM83579 DQ895892 ABM86818 EU794636 ACJ13690 M69066 AAA36322 XM_005262269 XP_005262326 XM_011530959 XP_011529261 XM_011530960 XP_011529262 NM_002444 NP_002435
Function	Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage. {ECO:0000269|PubMed:21549406}.
Subcellular Location	Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Apical cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell projection, microvillus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment. {ECO:0000250, ECO:0000269|PubMed:18586956}.
Tissue Specificity	In all tissues and cultured cells studied.
Top Pathways	Leukocyte transendothelial migration, Measles, Proteoglycans in cancer, Regulation of actin cytoskeleton

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SignalSilence ® Moesin siRNA I - 6499 from Cell Signaling Technology Category siRNA Prices $256.00 Sizes 300 µl (3 nmol) Species Reactivities Human

Moesin CRISPR/Cas9 KO Plasmid (h) - sc-401065 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Moesin HDR Plasmid (h) - sc-401065-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Moesin Double Nickase Plasmid (h) - sc-401065-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Moesin Double Nickase Plasmid (h2) - sc-401065-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Moesin CRISPR Activation Plasmid (h) - sc-401065-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Moesin CRISPR Activation Plasmid (h2) - sc-401065-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Moesin Lentiviral Activation Particles (h) - sc-401065-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Moesin Lentiviral Activation Particles (h2) - sc-401065-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Moesin siRNA (h) - sc-35955 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Moesin shRNA Plasmid (h) - sc-35955-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Moesin shRNA (h) Lentiviral Particles - sc-35955-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Moesin RNAi - H00004478-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU088931 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14657 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14657 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MSN siRNA (Human) - CRH2974 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

Moesin CRISPR/Cas9 KO Plasmid (h2) - sc-401065-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Moesin HDR Plasmid (h2) - sc-401065-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human MSN (NM_002444.2) - SHH345784 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human MSN(NM_002444.2) - SHH204041 from Creative biogene Category siRNA Species Reactivities Human

Human MSN siRNA - orb263476 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

MSN shRNA Plasmid (Human) - CHH2974 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

MSN miRNA 3'UTR clone - MiUTR1H-06481 from Creative biogene Species Reactivities Human

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