CDC20

Gene Symbol CDC20
Entrez Gene 991
Alt Symbol CDC20A, bA276H19.3, p55CDC
Species Human
Gene Type protein-coding
Description cell division cycle 20
Other Description CDC20 cell division cycle 20 homolog|cell division cycle 20 homolog|cell division cycle protein 20 homolog
Swissprots Q12834 Q9BW56 B2R6Z6 Q9UQI9 D3DPJ1 Q5JUY4
Accessions ABE96834 EAX07101 EAX07102 Q12834 AF099644 AAD16405 AK225504 AK302539 BAG63811 AK303844 BAG64787 AK312780 BAG35643 BC000624 AAH00624 BC001088 AAH01088 BC006272 AAH06272 BC009425 AAH09425 BC009426 AAH09426 BC010044 AAH10044 BC012803 AAH12803 BC012827 AAH12827 BC013303 AAH13303 BC015998 AAH15998 BC024257 AAH24257 BC031294 AAH31294 BC110321 AAI10322 BT007388 AAP36052 DQ892290 ABM83216 DQ895489 ABM86415 EU831627 ACE87227 EU831712 ACE86546 U05340 AAA19017 NM_001255 NP_001246
Function Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation. {ECO:0000269|PubMed:9637688, ECO:0000269|PubMed:9734353, ECO:0000269|PubMed:9811605}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20034488}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:20034488}.
Top Pathways Cell cycle, Ubiquitin mediated proteolysis, Oocyte meiosis, HTLV-I infection, Viral carcinogenesis

p55 CDC CRISPR/Cas9 KO Plasmid (h) - sc-400583 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

p55 CDC HDR Plasmid (h) - sc-400583-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

p55 CDC Double Nickase Plasmid (h) - sc-400583-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

p55 CDC Double Nickase Plasmid (h2) - sc-400583-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

p55 CDC CRISPR Activation Plasmid (h) - sc-400583-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

p55 CDC CRISPR Activation Plasmid (h2) - sc-400583-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

p55 CDC Lentiviral Activation Particles (h) - sc-400583-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

p55 CDC Lentiviral Activation Particles (h2) - sc-400583-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

p55 CDC siRNA (h) - sc-42008 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

p55 CDC shRNA Plasmid (h) - sc-42008-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

p55 CDC shRNA (h) Lentiviral Particles - sc-42008-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU106031 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5772 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5772 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CDC20 siRNA (Human) - CRH0706 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CDC20 - MBS8240783 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

p55 CDC CRISPR/Cas9 KO Plasmid (h2) - sc-400583-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

p55 CDC HDR Plasmid (h2) - sc-400583-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human CDC20 (NM_001255.2) - SHH259649 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CDC20(NM_001255.2) - SHG160441 from Creative biogene

Category siRNA
Species Reactivities Human

p55 CDC siRNA (h2) - sc-156154 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

p55 CDC shRNA Plasmid (h2) - sc-156154-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

p55 CDC shRNA (h2) Lentiviral Particles - sc-156154-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Human CDC20 siRNA - orb261208 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CDC20 shRNA Plasmid (Human) - CHH0706 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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