Gene Symbol |
Ust
|
Entrez Gene |
338362
|
Alt Symbol |
D930010O20Rik, UA2OST
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
uronyl-2-sulfotransferase
|
Other Description |
uronyl 2-sulfotransferase
|
Swissprots |
Q8BUB6 B2RR02
|
Accessions |
EDL03535 Q8BUB6 AK029782 AK086181 BAC39625 AK147850 AK162950 BAE37128 BC138155 AAI38156 XM_006512772 XP_006512835 NM_177387 NP_796361
|
Function |
Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues. Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity toward glucuronyl residues of chondroitin sulfate. Has no activity toward desulfated N-resulfated heparin (By similarity). {ECO:0000250}.
|
Subcellular Location |
Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
Top Pathways |
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
|