Gene Symbol | Ust |
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Entrez Gene | 338362 |
Alt Symbol | D930010O20Rik, UA2OST |
Species | Mouse |
Gene Type | protein-coding |
Description | uronyl-2-sulfotransferase |
Other Description | uronyl 2-sulfotransferase |
Swissprots | Q8BUB6 B2RR02 |
Accessions | EDL03535 Q8BUB6 AK029782 AK086181 BAC39625 AK147850 AK162950 BAE37128 BC138155 AAI38156 XM_006512772 XP_006512835 NM_177387 NP_796361 |
Function | Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues. Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity toward glucuronyl residues of chondroitin sulfate. Has no activity toward desulfated N-resulfated heparin (By similarity). {ECO:0000250}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Top Pathways | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate |
UST CRISPR/Cas9 KO Plasmid (m) - sc-436111 from Santa Cruz Biotechnology
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UST HDR Plasmid (m) - sc-436111-HDR from Santa Cruz Biotechnology
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UST Double Nickase Plasmid (m) - sc-436111-NIC from Santa Cruz Biotechnology
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UST Double Nickase Plasmid (m2) - sc-436111-NIC-2 from Santa Cruz Biotechnology
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UST CRISPR Activation Plasmid (m) - sc-436111-ACT from Santa Cruz Biotechnology
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UST CRISPR Activation Plasmid (m2) - sc-436111-ACT-2 from Santa Cruz Biotechnology
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UST Lentiviral Activation Particles (m) - sc-436111-LAC from Santa Cruz Biotechnology
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UST Lentiviral Activation Particles (m2) - sc-436111-LAC-2 from Santa Cruz Biotechnology
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UST siRNA (m) - sc-154949 from Santa Cruz Biotechnology
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UST shRNA Plasmid (m) - sc-154949-SH from Santa Cruz Biotechnology
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UST shRNA (m) Lentiviral Particles - sc-154949-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU059651 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN44046 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND44046 from Sigma-Aldrich
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UST siRNA (Mouse) - CRN4713 from Cohesion Biosciences
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UST - MBS8209314 from MyBioSource
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shRNA set against Mouse UST (NM_177387.3) - SHH441856 from Creative biogene
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shRNA set against Mouse Ust(NM_177387.3) - SHL119160 from Creative biogene
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UST shRNA Plasmid (Mouse) - CHN4713 from Cohesion Biosciences
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UST miRNA 3'UTR clone - MiUTR1M-12530 from Creative biogene
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