| Gene Symbol |
Chtop
|
| Entrez Gene |
361990
|
| Alt Symbol |
Fop, SRAG
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
similar to DKFZP547E1010 protein
|
| Other Description |
Friend of PRMT1 protein|chromatin target of PRMT1 protein|small arginine- and glycine-rich protein
|
| Swissprots |
Q66H75 Q498T2
|
| Accessions |
EDM00557 EDM00558 EDM00559 Q498T2 BC081985 AAH81985 BC100084 AAI00085 FQ231784 XM_006232710 XP_006232772 XM_006232711 XP_006232773 XM_006232713 XP_006232775 XM_006232715 XP_006232777 XR_591190 XR_591191 NM_001014175 NP_001014197
|
| Function |
Plays an important role in the ligand-dependent activation of estrogen receptor target genes. May play a role in the silencing of fetal globin genes. Recruits the 5FMC complex to ZNF148, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Nucleus, nucleoplasm {ECO:0000250}. Note=Mostly associated with facultative heterochromatin. {ECO:0000250}.
|