| Gene Symbol | Chtop |
|---|---|
| Entrez Gene | 361990 |
| Alt Symbol | Fop, SRAG |
| Species | Rat |
| Gene Type | protein-coding |
| Description | similar to DKFZP547E1010 protein |
| Other Description | Friend of PRMT1 protein|chromatin target of PRMT1 protein|small arginine- and glycine-rich protein |
| Swissprots | Q66H75 Q498T2 |
| Accessions | EDM00557 EDM00558 EDM00559 Q498T2 BC081985 AAH81985 BC100084 AAI00085 FQ231784 XM_006232710 XP_006232772 XM_006232711 XP_006232773 XM_006232713 XP_006232775 XM_006232715 XP_006232777 XR_591190 XR_591191 NM_001014175 NP_001014197 |
| Function | Plays an important role in the ligand-dependent activation of estrogen receptor target genes. May play a role in the silencing of fetal globin genes. Recruits the 5FMC complex to ZNF148, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (By similarity). {ECO:0000250}. |
| Subcellular Location | Nucleus {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Nucleus, nucleoplasm {ECO:0000250}. Note=Mostly associated with facultative heterochromatin. {ECO:0000250}. |
CompoZr® Knockout ZFN Kit - CKOZFN56356 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND56356 from Sigma-Aldrich
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CHTOP siRNA (Rat) - CRR5954 from Cohesion Biosciences
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CHTOP - MBS8241338 from MyBioSource
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shRNA set against Rat LOC361990 (NM_001014175.1) - SHH331931 from Creative biogene
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Rat CHTOP siRNA - orb300803 from Biorbyt
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CHTOP shRNA Plasmid (Rat) - CHR5954 from Cohesion Biosciences
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LOC361990 miRNA 3'UTR clone - MiUTR1R-03225 from Creative biogene
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