ATP5A1

Gene Symbol	ATP5A1
Entrez Gene	100157880
Alt Symbol	ATP5A2
Species	Pig
Gene Type	protein-coding
Description	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
Other Description	ATP synthase subunit alpha heart isoform, mitochondrial|ATP synthase subunit alpha liver isoform, mitochondrial|ATP synthase subunit alpha, mitochondrial|cardiac muscle ATP synthase H+ transporting mitochondrial F1 complex alpha subunit 1
Swissprots	Q29596 B2ZF46 P80021
Accessions	P80021 AK232528 AK236714 AK238748 AK239102 AK397056 AY609645 EU650784 ACD02421 NM_001185142 NP_001172071
Function	Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity). {ECO:0000250}.
Subcellular Location	Mitochondrion inner membrane {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Extracellular side {ECO:0000250}. Note=Colocalizes with HRG on the cell surface of T-cells. {ECO:0000250}.
Tissue Specificity	Expressed in heart (at protein level). Detected in liver.
Top Pathways	Alzheimer's disease, Huntington's disease, Oxidative phosphorylation

• Assays/Kits
• Proteins/Peptides

ATP synthase subunit alpha, mitochondrial (ATP5A1), Pig, ELISA Kit - CSB-EL002344PI from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

ATP synthase subunit alpha, mitochondrial (ATP5A1), Porcine, ELISA Kit - E07A1759 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle, ELISA Kit - MBS909312 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of pig ATP5A1 is typically less than 7 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 28 pg/ml -1800 pg/ml.

Pig ATP synthase subunit alpha, mitochondrial(ATP5A1) ELISA kit - CSB-EL002344PI from Cusabio Category ELISA Kit Sensitivity 7 pg/ml. Range 28 pg/ml-1800 pg/ml

Pig ATP synthase subunit alpha, mitochondrial (ATP5A1) ELISA Kit - EKC38101 from Biomatik Category ELISA Kit Prices $795.00, $3,021.00, $5,645.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 7 pg/ml Range 28 pg/ml-1800 pg/ml

Porcine ATP5A1 ELISA Kit - E076169 from Biobool Category ELISA Kit

ATP5A1 ELISA Kit (Pig) (OKCA01801) - OKCA01801 from Aviva Systems Biology Category ELISA Kit Prices $665.00 Sizes 96 wells Sensitivity 7 pg/mL Range 28 - 1,800 pg/mL

Pig ATP5A1 ELISA Kit - orb409583 from Biorbyt Category ELISA Kit Sensitivity 7 pg/ml. Range 28 pg/ml-1800 pg/ml

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