DSE

Gene Symbol DSE
Entrez Gene 29940
Alt Symbol DSEP, DSEPI, EDSMC2, SART-2, SART2
Species Human
Gene Type protein-coding
Description dermatan sulfate epimerase
Other Description DS epimerase|chondroitin-glucuronate 5-epimerase|dermatan-sulfate epimerase|squamous cell carcinoma antigen recognized by T-cells 2
Swissprots Q9UL01 Q5R3K6
Accessions EAW48229 EAW48230 Q9UL01 AF098066 AAF00087 AK095123 AK128607 BAG54699 AK293872 BAH11619 AK301513 BAH13501 AL832471 BC039245 AAH39245 BC043526 DB282412 DQ891261 ABM82187 DQ894447 ABM85373 XM_011535785 XP_011534087 NM_001080976 NP_001074445 NM_013352 NP_037484
Function Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues. {ECO:0000269|PubMed:16505484}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Ubiquitously expressed with higher expression in kidney and ovary and lower expression in brain, colon and thymus. Also expressed in renal cell carcinomas, brain tumors, and in a part of melanomas and adenocarcinomas from organs other than the breast. Expressed in squamous cell carcinomas (SCC), glioma, and some adenocarcinoma cell lines, but not in breast cancer cell lines or any normal tissues (at protein level). {ECO:0000269|PubMed:10679095}.
Top Pathways Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

SART2 293T Cell Transient Overexpression Lysate(Denatured) - H00029940-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

SART2 Overexpression Lysate (Denatured) - H00029940-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
Lane 1: DSE transfected lysate (105.49 KDa) Lane 2: Non-transfected lysate.

Panoply™ Human DSE Knockdown Stable Cell Line - CSC-DC004563 from Creative biogene

Category Cell Line
Species Human
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