DSE

Gene Symbol DSE
Entrez Gene 29940
Alt Symbol DSEP, DSEPI, EDSMC2, SART-2, SART2
Species Human
Gene Type protein-coding
Description dermatan sulfate epimerase
Other Description DS epimerase|chondroitin-glucuronate 5-epimerase|dermatan-sulfate epimerase|squamous cell carcinoma antigen recognized by T-cells 2
Swissprots Q9UL01 Q5R3K6
Accessions EAW48229 EAW48230 Q9UL01 AF098066 AAF00087 AK095123 AK128607 BAG54699 AK293872 BAH11619 AK301513 BAH13501 AL832471 BC039245 AAH39245 BC043526 DB282412 DQ891261 ABM82187 DQ894447 ABM85373 XM_011535785 XP_011534087 NM_001080976 NP_001074445 NM_013352 NP_037484
Function Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues. {ECO:0000269|PubMed:16505484}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Ubiquitously expressed with higher expression in kidney and ovary and lower expression in brain, colon and thymus. Also expressed in renal cell carcinomas, brain tumors, and in a part of melanomas and adenocarcinomas from organs other than the breast. Expressed in squamous cell carcinomas (SCC), glioma, and some adenocarcinoma cell lines, but not in breast cancer cell lines or any normal tissues (at protein level). {ECO:0000269|PubMed:10679095}.
Top Pathways Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

SART2 CRISPR/Cas9 KO Plasmid (h) - sc-407069 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SART2 HDR Plasmid (h) - sc-407069-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SART2 Double Nickase Plasmid (h) - sc-407069-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SART2 Double Nickase Plasmid (h2) - sc-407069-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SART2 CRISPR Activation Plasmid (h) - sc-407069-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SART2 CRISPR Activation Plasmid (h2) - sc-407069-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SART2 Lentiviral Activation Particles (h) - sc-407069-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SART2 Lentiviral Activation Particles (h2) - sc-407069-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SART2 siRNA (h) - sc-95481 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SART2 shRNA Plasmid (h) - sc-95481-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SART2 shRNA (h) Lentiviral Particles - sc-95481-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SART2 RNAi - H00029940-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU115501 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7506 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7506 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07728 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07728

DSE siRNA (Human) - CRH9282 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SART2 RNAi - H00029940-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

DSE - MBS8215205 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SART2 CRISPR/Cas9 KO Plasmid (h2) - sc-407069-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SART2 HDR Plasmid (h2) - sc-407069-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human DSE (NM_013352.2) - SHH281225 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human DSE(NM_001080976.1) - SHH016535 from Creative biogene

Category siRNA
Species Reactivities Human

Human DSE siRNA - orb269784 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DSE shRNA Plasmid (Human) - CHH9282 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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