EMG1

Gene Symbol	EMG1
Entrez Gene	10436
Alt Symbol	C2F, Grcc2f, NEP1
Species	Human
Gene Type	protein-coding
Description	EMG1 N1-specific pseudouridine methyltransferase
Other Description	18S rRNA (pseudouridine(1248)-N1)-methyltransferase|18S rRNA (pseudouridine-N1-)-methyltransferase NEP1|18S rRNA Psi1248 methyltransferase|EMG1 nucleolar protein homolog|essential for mitotic growth 1|ribosomal RNA small subunit methyltransferase NEP1|ribosome biogenesis protein NEP1
Swissprots	O00726 Q92979 O00675
Accessions	AAB51325 EAW88694 EAW88695 EAW88696 EAW88697 EAW88698 Q92979 AA314580 AI394112 AK291597 BAF84286 AK298207 BAG60477 AK298745 BAG60889 AK307177 BC055314 AAH55314 BM709304 BQ015307 CD704778 DA070200 DC403138 HQ447756 ADQ32241 U56427 U72514 AAC51641 XM_011520907 XP_011519209 NM_006331 NP_006322
Function	S-adenosyl-L-methionine-dependent pseudouridine N(1)- methyltransferase that methylates pseudouridine at position 1248 (Psi1248) in 18S rRNA. Involved the biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA. Is not able to methylate uridine at this position (PubMed:20047967). Has also an essential role in 40S ribosomal subunit biogenesis independent on its methyltransferase activity, facilitating the incorporation of ribosomal protein S19 during the formation of pre-ribosomes (By similarity). {ECO:0000250|UniProtKB:Q06287, ECO:0000269|PubMed:20047967}.
Subcellular Location	Nucleus, nucleolus {ECO:0000269|PubMed:11935223}.
Top Pathways	Ribosome biogenesis in eukaryotes

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human EMG1 full length protein - ab130059 from Abcam Category Protein Source E. coli Species Human

EMG1 / NEP1 Antibody Blocking Peptide - LS-E775 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EMG1 / NEP1 Antibody Blocking Peptide - LS-E14868 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human EMG1 Protein - NBP1-98914 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

EMG1-Antibody-Center-Blocking-peptide - BP11129c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human EMG1 protein - orb168290 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

EMG1 Blocking Peptide - 33R-8582 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

EMG1 protein (His tag) - 80R-2360 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

EMG1 / C2F (1-244, His-tag) - AR50441PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

EMG1 / C2F (1-244, His-tag) - AR50441PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

EMG1 / C2F - P5850 from Acris Antibodies Category Protein Prices $500.00 Sizes 100 µg Species Human

EMG1, 1-244aa, Human, His tag, E.coli - 01-P1617 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

EMG1 fusion protein - Ag2575 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

EMG1 Human - PRPS-1129 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source E.coli. Species Human

Recombinant Human EMG1 Nucleolar Protein - BP002886-PRO-1122 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

EMG1, 1-244aa, Recombinant Protein - GWB-P0421E from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human EMG1 Nucleolar Protein Homolog(S. cerevisiae), His-tagged - EMG1-6938H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human Ribosomal RNA small subunit methyltransferase NEP1(EMG1) - CSB-YP852924HU CSB-EP852924HU CSB-BP852924HU CSB-MP852924HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

EMG1, 1-244aa, Human, His tag, E.coli - ATGP1617 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

EMG1 / C2F - TP308885 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

EMG1 Peptide, Human - M34GP04903H from Creative Peptides Category Peptide Source Synthetic. Species Human

EMG1 - PAT-81657-1 from Nordic BioSite Category Protein Species Human

EMG1 - PAT-81657-2 from Nordic BioSite Category Protein Species Human

EMG1 Recombinant Protein Antigen - NBP2-54688PEP from Novus Biologicals Category Protein Prices $229.00 Sizes 100 µl Source E.coli Species Human

EMG1 Recombinant Protein Antigen - NBP2-55324PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

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