| Gene Symbol |
Acadsb
|
| Entrez Gene |
66885
|
| Alt Symbol |
1300003O09Rik, BB066609
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
acyl-Coenzyme A dehydrogenase, short/branched chain
|
| Other Description |
2-MEBCAD|2-methyl branched chain acyl-CoA dehydrogenase|2-methylbutyryl-CoA dehydrogenase|2-methylbutyryl-coenzyme A dehydrogenase|SBCAD|short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
|
| Swissprots |
Q9DBL1
|
| Accessions |
EDL17713 EDL17714 EDL17715 Q9DBL1 AK004889 BAB23646 AK076535 AK078636 AK131628 BAE20728 AK152325 AK163322 BAE37299 AW987640 BC011235 BC035231 BC044826 BC054428 AAH54428 BY296718 NM_025826 NP_080102
|
| Function |
Has greatest activity toward short branched chain acyl- CoA derivative such as (s)-2-methylbutyryl-CoA, isobutyryl-CoA, and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. Can use valproyl- CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this agent (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion matrix {ECO:0000305}.
|
| Top Pathways |
Fatty acid degradation, Valine, leucine and isoleucine degradation, Fatty acid metabolism
|