Gene Symbol | Acadsb |
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Entrez Gene | 66885 |
Alt Symbol | 1300003O09Rik, BB066609 |
Species | Mouse |
Gene Type | protein-coding |
Description | acyl-Coenzyme A dehydrogenase, short/branched chain |
Other Description | 2-MEBCAD|2-methyl branched chain acyl-CoA dehydrogenase|2-methylbutyryl-CoA dehydrogenase|2-methylbutyryl-coenzyme A dehydrogenase|SBCAD|short/branched chain specific acyl-CoA dehydrogenase, mitochondrial |
Swissprots | Q9DBL1 |
Accessions | EDL17713 EDL17714 EDL17715 Q9DBL1 AK004889 BAB23646 AK076535 AK078636 AK131628 BAE20728 AK152325 AK163322 BAE37299 AW987640 BC011235 BC035231 BC044826 BC054428 AAH54428 BY296718 NM_025826 NP_080102 |
Function | Has greatest activity toward short branched chain acyl- CoA derivative such as (s)-2-methylbutyryl-CoA, isobutyryl-CoA, and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. Can use valproyl- CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this agent (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion matrix {ECO:0000305}. |
Top Pathways | Fatty acid degradation, Valine, leucine and isoleucine degradation, Fatty acid metabolism |
ACADSB CRISPR/Cas9 KO Plasmid (m) - sc-426247 from Santa Cruz Biotechnology
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ACADSB HDR Plasmid (m) - sc-426247-HDR from Santa Cruz Biotechnology
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ACADSB Double Nickase Plasmid (m) - sc-426247-NIC from Santa Cruz Biotechnology
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ACADSB Double Nickase Plasmid (m2) - sc-426247-NIC-2 from Santa Cruz Biotechnology
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ACADSB CRISPR Activation Plasmid (m) - sc-426247-ACT from Santa Cruz Biotechnology
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ACADSB CRISPR Activation Plasmid (m2) - sc-426247-ACT-2 from Santa Cruz Biotechnology
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ACADSB Lentiviral Activation Particles (m) - sc-426247-LAC from Santa Cruz Biotechnology
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ACADSB Lentiviral Activation Particles (m2) - sc-426247-LAC-2 from Santa Cruz Biotechnology
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ACADSB siRNA (m) - sc-140793 from Santa Cruz Biotechnology
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ACADSB shRNA Plasmid (m) - sc-140793-SH from Santa Cruz Biotechnology
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ACADSB shRNA (m) Lentiviral Particles - sc-140793-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN26121 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26121 from Sigma-Aldrich
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ACADSB siRNA (Mouse) - CRM6865 from Cohesion Biosciences
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ACADSB - MBS8224347 from MyBioSource
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shRNA set against Mouse ACADSB (NM_025826.4) - SHH229954 from Creative biogene
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Mouse ACADSB siRNA - orb286341 from Biorbyt
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ACADSB shRNA Plasmid (Mouse) - CHM6865 from Cohesion Biosciences
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