CD68

Gene Symbol	CD68
Entrez Gene	968
Alt Symbol	GP110, LAMP4, SCARD1
Species	Human
Gene Type	protein-coding
Description	CD68 molecule
Other Description	CD68 antigen|macrophage antigen CD68|macrosialin|scavenger receptor class D, member 1
Swissprots	P34810 Q53XI3 Q53HR6 Q96BI7 B4DVT4
Accessions	AAC70006 EAW90165 P34810 AK222492 BAD96212 AK222514 BAD96234 AK290238 BAF82927 AK298055 BAG60349 AK301223 BAG62796 AW294871 BC015557 AAH15557 BT009923 AAP88925 BX438711 BX647524 DB187273 DQ890631 ABM92248 DQ893801 ABM84727 S57235 AAB25811 NM_001040059 NP_001035148 NM_001251 NP_001242
Function	Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Subcellular Location	Isoform Short: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. {ECO:0000269|PubMed:18405323}.
Top Pathways	Lysosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CD68 full length protein - ab38260 from Abcam Category Protein Prices $297.00 Sizes 10 µg Source E. coli Species Human

Human CD68 peptide - ab66690 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human CD68 protein fragment - ab134533 from Abcam Category Protein Prices $345.00 Sizes 50 µg Source E. coli Species Human

Human CD68 protein fragment - ab174015 from Abcam Category Protein Prices $350.00 Sizes 100 µg Source HEK 293 cells Species Human

CD68 Antibody Blocking Peptide - LS-E4995 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CD68 Antibody Blocking Peptide - LS-E22988 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CD68 Antibody Blocking Peptide - LS-E22989 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CD68/SR-D1 Partial Recombinant Protein - H00000968-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human CD68/SR-D1 Protein - NBP2-22756 from Novus Biologicals Category Protein Prices $349.00 Sizes 50 µg Species Human

CD68/SR-D1 Recombinant Protein - H00000968-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

CD68/SR-D1 Recombinant Protein - P4859 from Novus Biologicals Category Protein Prices $799.00 Sizes 10 µg Species Human

CD68CD68-kpi-Antibody-Center-Blocking-Peptide - BP17393c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CD68-Antibody-N-term-Blocking-Peptide - BP8870a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CD68 Protein (OPPA01210) - OPPA01210 from Aviva Systems Biology Category Protein Prices $315.00 Sizes 2 µg Source E. Coli

Human CD68, 38kDa protein - orb81012 from Biorbyt Category Protein Prices $366.00, $400.00, $612.00 Sizes 5 μg, 2 μg, 10 μg Species Human

Human CD68 protein - orb168079 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 2 μg, 10 μg Source E.coli Species Human

Human CD68 protein - orb78505 from Biorbyt Category Protein Prices $255.00, $391.00, $519.00 Sizes 10 μg, 50 μg, 100 μg Species Human

CD68 peptide - orb72496 from Biorbyt Category Peptide Prices $238.00 Sizes 500 µg

CD68 protein (His tag) - 80R-2458 from Fitzgerald Category Protein Prices $365.00 Sizes 50 µg Source E.coli

CD68 Blocking Peptide - abx161328 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

CD68 (22-319, His-tag) - AR50530PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli Species Human

CD68 (22-319, His-tag) - AR50530PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

CD68 - H00000968-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CD68 - H00000968-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CD68 - H00000968-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Search more