ITGAL

Gene Symbol ITGAL
Entrez Gene 3683
Alt Symbol CD11A, LFA-1, LFA1A
Species Human
Gene Type protein-coding
Description integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
Other Description CD11 antigen-like family member A|LFA-1 alpha|LFA-1A|antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide|integrin alpha-L|integrin gene promoter|leukocyte adhesion glycoprotein LFA-1 alpha chain|leukocyte function-associated molecule 1 alpha chain|lymphocyte function-associated antigen 1
Swissprots Q9UBC8 O43746 Q96HB1 Q45H73 P20701
Accessions AAA16474 AAC31672 AAZ38713 CAA80461 EAW52243 EAW52244 EAW52245 P20701 AK298674 BAG60839 AK303190 BAG64283 AK314246 BAG36913 BC008777 AAH08777 CA430398 DC324373 Y00796 CAA68747 XM_005255313 XP_005255370 XM_006721044 XP_006721107 XM_011545849 XP_011544151 XR_950794 NM_001114380 NP_001107852 NM_002209 NP_002200
Function Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Leukocytes.
Top Pathways Malaria, Rap1 signaling pathway, Epstein-Barr virus infection, HTLV-I infection, Rheumatoid arthritis

Integrin αL (E-1) - sc-374172 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Integrin αL (E-1): sc-374172. Western blot analysis of Integrin αL expression in THP-1 (A) and CCRF-CEM (B) whole cell lysates.

Integrin αL (C-11) - sc-373938 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Integrin αL (C-11): sc-373938. Western blot analysis of Integrin αL expression in THP-1 whole cell lysate.

Integrin αL (N-18) - sc-6609 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Integrin αL (N-18): sc-6609. Immunofluorescence staining of methanol-fixed THP-1 cells showing membrane staining.

Integrin αL (H-300) - sc-15327 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Integrin αL (H-300): sc-15327. Immunofluorescence staining of methanol-fixed THP-1 cells showing membrane and cell junction localization.

Integrin αL (C-17) - sc-6608 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Integrin αL (C-17): sc-6608. Western blot analysis of Integrin αL expression in THP-1 whole cell lysate.

Integrin αL (F-11) - sc-373861 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Integrin αL (F-11): sc-373861. Western blot analysis of Integrin αL expression in CCRF-CEM whole cell lysate.

Integrin αL (38) - sc-7306 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Integrin αL (38) FITC: sc-7306 FITC. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG<sub>2a</sub>: sc-2856.

Integrin αL (16B8) - sc-18830 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Integrin αL (16B8): sc-18830. Immunofluorescence staining of methanol-fixed THP-1 cells showing membrane and cell junction localization.

Integrin αL (HI111) - sc-19647 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Integrin αL (HI111) PE: sc-19647 PE. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2866.

Integrin αL (CRIS-3) - sc-59741 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Integrin αL (CRIS-3): sc-59741. Western blot analysis of Integrin αL expression in human thymus tissue extract under non-reducing conditions.

Integrin αL (27) - sc-135951 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
Integrin αL (27): sc-135951. Western blot analysis of Integrin αL expression in Jurkat whole cell lysate.

Integrin αL/M/X/β2 (24) - sc-53359 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Anti-CD11+CD18 antibody [24] - ab13219 from Abcam

Prices $394.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 24
ab13219 staining CD11 + CD18 in Mouse splenocytes by Flow Cytometry. Cells were prepared in PBS + 1% BSA. The sample was incubated with the primary antibody (1/100 in PBS + 1% BSA) for 1 hour at 4°C. A FITC-conjugated Goat anti-mouse polyclonal (1/200) was used as the secondary antibody.

Anti-CD11+CD18 antibody [24] (FITC) - ab187835 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 24

Anti-CD11a antibody - ab186873 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD11a antibody (ab186873) at 1/500 dilutionLane 1 : Jurkat cell line extractLane 2 : A549 cell line extractLane 3 : Sw620 cell line extractLane 4 : Raji cell line extractLane 5 : HO-8910 cell line extractLane 6 : HepG2 cell line extractLane 7 : U937 cell line extractLane 8 : Mouse spleen cell line extract

Anti-CD11a antibody - ab89725 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD11a antibody (ab89725) at 1 µg/mlLane 1 : Thymus (Human) Tissue Lysate - adult normal tissue (ab30146)Lane 2 : Spleen (Human) Tissue Lysate - adult normal tissue (ab29699)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) (ab65484) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-CD11a antibody - ab203336 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin embedded Human breast carcinoma tissue labeling CD11a with ab203336 at 1/200 dilution, followed by secondary detection and DAB staining.

Anti-CD11a antibody - ab78058 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD11a antibody (ab78058) at 1 µg/mlLane 1 : Thymus (Human) Tissue Lysate - adult normal tissue (ab30146)Lane 2 : Spleen (Human) Tissue Lysate - adult normal tissue (ab29699)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-CD11a antibody - ab116579 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CD11a antibody (ab116579) at 1/100 dilution + Jurkat cell line lysate at 35 µg

Anti-CD11a antibody [38] - ab34214 from Abcam

Prices $379.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 38
Ab34214, at a dilution of 1/50 - 1/100, staining CD11a in human peripheral blood lymphocytes by Flow Cytometry.

Anti-CD11a antibody [38] - ab6132 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 38

Anti-CD11a antibody [38] (FITC) - ab34198 from Abcam

Prices $437.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 38
ab34198, Using 10ul of neat antibody, Staining of human peripheral blood lymphocytes by Flow Cytometry.

Anti-CD11a antibody [87-6F9] - ab23613 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 87-6F9

Anti-CD11a antibody [B-B15] - ab27386 from Abcam

Prices $378.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone B-B15
Staining pattern of lymphocytes with ab27386.

Anti-CD11a antibody [B-B15] - ab47202 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-B15
A typical staining pattern using ab47202 of lymphocytes.
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