| Gene Symbol |
Ghr
|
| Entrez Gene |
25235
|
| Alt Symbol |
GHR/BP
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
growth hormone receptor
|
| Other Description |
GH receptor|growth hormone receptor precursor splice variant D56|growth hormone receptor variant d5-6|growth hormone receptor/binding protein|somatotropin receptor
|
| Swissprots |
Q64236 Q80XW9 P16310
|
| Accessions |
AAC52917 AAP31905 EDL75743 EDL75744 EDL75745 P16310 BC086591 AAH86591 BC103659 AAI03660 BC127501 AAI27502 BC161852 FQ216498 FQ219220 J04811 AAA41219 JF330099 AEZ52406 JF412704 AEA34991 S49003 AAP13886 Z83757 XM_008760752 XP_008758974 XM_008760753 XP_008758975 XM_008760754 XP_008758976 NM_017094 NP_058790
|
| Function |
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.
|
| Subcellular Location |
Growth hormone-binding protein: Secreted {ECO:0000250}. Note=Complexed to a substantial fraction of circulating GH. {ECO:0000250}.
|
| Tissue Specificity |
Highest expression in liver. Also expressed in heart, kidney and muscle.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, PI3K-Akt signaling pathway, Neuroactive ligand-receptor interaction
|