| Gene Symbol | Ghr |
|---|---|
| Entrez Gene | 25235 |
| Alt Symbol | GHR/BP |
| Species | Rat |
| Gene Type | protein-coding |
| Description | growth hormone receptor |
| Other Description | GH receptor|growth hormone receptor precursor splice variant D56|growth hormone receptor variant d5-6|growth hormone receptor/binding protein|somatotropin receptor |
| Swissprots | Q64236 Q80XW9 P16310 |
| Accessions | AAC52917 AAP31905 EDL75743 EDL75744 EDL75745 P16310 BC086591 AAH86591 BC103659 AAI03660 BC127501 AAI27502 BC161852 FQ216498 FQ219220 J04811 AAA41219 JF330099 AEZ52406 JF412704 AEA34991 S49003 AAP13886 Z83757 XM_008760752 XP_008758974 XM_008760753 XP_008758975 XM_008760754 XP_008758976 NM_017094 NP_058790 |
| Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway. |
| Subcellular Location | Growth hormone-binding protein: Secreted {ECO:0000250}. Note=Complexed to a substantial fraction of circulating GH. {ECO:0000250}. |
| Tissue Specificity | Highest expression in liver. Also expressed in heart, kidney and muscle. |
| Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, PI3K-Akt signaling pathway, Neuroactive ligand-receptor interaction |
CompoZr® Knockout ZFN Kit - CKOZFN54414 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND54414 from Sigma-Aldrich
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GHR siRNA (Rat) - CRR0506 from Cohesion Biosciences
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GHR - MBS8205225 from MyBioSource
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shRNA set against Rat Ghr (NM_017094.1) - SHH300970 from Creative biogene
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shRNA set against Rat Ghr(NM_017094.1) - SHH083981 from Creative biogene
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Rat GHR siRNA - orb295355 from Biorbyt
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GHR shRNA Plasmid (Rat) - CHR0506 from Cohesion Biosciences
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GHR miRNA 3'UTR clone - MiUTR1R-02098 from Creative biogene
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