CDC25B

Gene Symbol CDC25B
Entrez Gene 994
Alt Symbol -
Species Human
Gene Type protein-coding
Description cell division cycle 25B
Other Description M-phase inducer phosphatase 2|dual specificity phosphatase Cdc25B
Swissprots Q5JX77 O43551 D3DVY1 P30305 D3DVY2 Q13971 D3DVY4 Q6RSS1 D3DVY3 Q9BRA6
Accessions AAB94622 AAB94623 AAB94624 AAB94625 AAR26469 CAA65303 EAX10491 EAX10493 EAX10494 EAX10496 EAX10498 EAX10499 EAX10500 EAX10501 P30305 AK092713 BAG52600 AK124284 AK295573 BAG58472 AK299028 BAG61105 AK299192 BAG61235 AL561439 BC006395 AAH06395 BC009953 AAH09953 BC051711 AAH51711 BM793120 BX640836 CAE45909 BX647988 DA065196 DA107932 DB477384 FR695900 CBX26628 FR695901 CBX26629 M81934 AAA58416 S78187 AAB21139 Z68092 CAA92108 XR_937181 NM_001287516 NP_001274445 NM_001287517 NP_001274446 NM_001287518 NP_001274447 NM_001287519 NP_001274448 NM_001287520 NP_001274449 NM_001287522 NP_001274451 NM_001287524 NP_001274453 NM_004358 NP_004349 NM_021872 NP_068658 NM_021873 NP_068659 NM_021874 NM_212530
Function Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity. {ECO:0000269|PubMed:17332740}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole.
Top Pathways Cell cycle, Progesterone-mediated oocyte maturation, MAPK signaling pathway, MicroRNAs in cancer

cdc25B Antibody - 9525 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HT29 cells, untreated (lane 1), hydroxyurea-treated (2 mM, G1/S, lane 2), and nocodazole-treated (50 ng/ml, M, lane 3), using cdc25B Antibody.

Cdc25B (E-19) - sc-6948 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Cdc25B (E-19): sc-6948. Western blot analysis of Cdc25B expression in HEL 92.1.7 (A), HL-60 (B), K-562 (C), THP-1 (D) and U-937 (E) whole cell lysates.

Cdc25B (DCS-164) - sc-65504 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Cdc25B (N-19) - sc-6949 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Cdc25B (H-85) - sc-5619 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Cdc25B (H-85): sc-5619. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear and cytoplasmic localization.

Cdc25B (DCS-162) - sc-56266 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Cdc25B (C-20) - sc-326 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Cdc25B (C-20): sc-326. Immunoperoxidase staining of formalin-fixed, paraffin-embedded mouse liver tissue showing nuclear and cytoplasmic localization.

Cdc25B (SPM170) - sc-56357 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Cdc25B (3F116) - sc-70825 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

p-Cdc25B (Ser 187 ) - sc-130184 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-Cdc25B (Ser 187 ): sc-130184. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.

Anti-Cdc25B (phospho S187) antibody - ab59986 from Abcam

Prices $304.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Cdc25B (phospho S187) antibody (ab59986) at 1/100 dilution + SK-BR-3 cell lysate

Anti-Cdc25B (phospho S323) antibody - ab53103 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cdc25B (phospho S323) antibody (ab53103) at 1/300 dilutionLane 1 : NIH/3T3 cell extract treated with PMA (125ng/ml, 30 mins)Lane 2 : NIH/3T3 cell extract treated with PMA (125ng/ml, 30 mins) and the immunogenic phosphopeptide.

Anti-Cdc25B (phospho S353) antibody - ab135547 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-Cdc25B (phospho S353) antibody (ab135547) at 1/100 dilution + HepG2 cell lysate at 12.5 µg

Anti-Cdc25B (phospho S353) antibody - ab59431 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab59431, at a 1/50 dilution, staining paraffin embedded human brain tissue sections by Immunohistochemistry in the absence (left image) or presence (right image) of the phosphopeptide.

Anti-Cdc25B antibody - ab70927 from Abcam

Prices $385.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Cdc25B antibody (ab70927) at 1/50 dilution + Ramos cell line lysates at 12.5 µg

Anti-Cdc25B antibody - ab125228 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Cdc25B antibody - ab167347 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Cdc25B antibody (ab167347) at 1 µg/mlLane 1 : Cdc25B transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.

Anti-Cdc25B antibody - ab63220 from Abcam

Prices $304.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Cdc25B antibody (ab63220) at 1/60 dilution + A2058 cell line lysate at 35 µg

Anti-Cdc25B antibody - ab76098 from Abcam

Prices $304.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Cdc25B antibody (ab76098) at 1/50 dilution + Ramos cell line lysate at 35 µg

Anti-Cdc25B antibody - ab59391 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using ab59391 at a 1/50 dilution. Left image: un-treated. Right image: treated with peptide.

Anti-Cdc25B antibody - ab136130 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Cdc25B antibody (ab136130) at 1/500 dilution + HeLa cell lysate

Anti-Cdc25B antibody - ab32000 from Abcam

Host Chicken
Clonality Polyclonal
Anti-Cdc25B antibody (ab32000) at 1/2000 dilution + E coli-derived fusion protein at 1 µgSecondaryGoat anti-IgY-HRP at 1/1000 dilution

Anti-Cdc25B antibody [DCS-162] - ab2358 from Abcam

Prices $378.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone DCS-162

Anti-Cdc25B antibody [EPR3459(2)] - ab124819 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3459(2)
All lanes : Anti-Cdc25B antibody [EPR3459(2)] (ab124819) at 1/1000 dilutionLane 1 : K562 cell lysateLane 2 : U937 cell lysateLane 3 : THP-1 cell lysate Lysates/proteins at 10 µg per lane.SecondaryGoat-anti-rabbit HRP at 1/2000 dilution

Anti-CDC25B Antibody (C-Terminus) - LS-C5920 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Search more