SLC12A7

Gene Symbol SLC12A7
Entrez Gene 10723
Alt Symbol KCC4
Species Human
Gene Type protein-coding
Description solute carrier family 12 (potassium/chloride transporter), member 7
Other Description K-Cl cotransporter 4|electroneutral potassium-chloride cotransporter 4|potassium/chloride transporter KCC4|solute carrier family 12 (potassium/chloride transporters), member 7|solute carrier family 12 member 7
Swissprots A6NDS8 Q9H7I3 Q9Y666 Q4G0F3 Q9H7I7 Q9UFW2 Q96I81
Accessions CAH25944 EAX08178 EAX08179 EAX08180 EAX08181 Q9Y666 AF105365 AAD39741 AK024493 BAB15783 AK024497 BAB15787 AK026625 AK302856 BAG64042 AL117433 CAB55921 BC007760 AAH07760 BC018982 BC098390 AAH98390 BU953746 DB451347 XM_005248231 XP_005248288 XM_006725006 XP_006725069 XM_011513939 XP_011512241 XM_011513940 XP_011512242 XM_011513941 XP_011512243 XM_011546472 XP_011544774 XM_011546473 XP_011544775 XM_011546474 XP_011544776 XR_925579 XR_925580 XR_925582 XR_951676 XR_951677 XR_951678 NM_006598 NP_006589
Function Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Detected in muscle, brain, lung, heart and kidney.
Top Pathways Collecting duct acid secretion

KCC4 CRISPR/Cas9 KO Plasmid (h) - sc-405528 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCC4 HDR Plasmid (h) - sc-405528-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCC4 Double Nickase Plasmid (h) - sc-405528-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCC4 Double Nickase Plasmid (h2) - sc-405528-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCC4 CRISPR Activation Plasmid (h) - sc-405528-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCC4 CRISPR Activation Plasmid (h2) - sc-405528-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCC4 Lentiviral Activation Particles (h) - sc-405528-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCC4 Lentiviral Activation Particles (h2) - sc-405528-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCC4 siRNA (h) - sc-42610 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KCC4 shRNA Plasmid (h) - sc-42610-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KCC4 shRNA (h) Lentiviral Particles - sc-42610-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KCC4/SLC12A7 RNAi - H00010723-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU134511 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19408 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19408 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10993 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10993

SLC12A7 siRNA (Human) - CRH7305 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC12A7 - MBS8217299 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SLC12A7 (NM_006598.2) - SHH408372 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SLC12A7(NM_006598.2) - SHR228588 from Creative biogene

Category siRNA
Species Reactivities Human

Human SLC12A7 siRNA - orb267807 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC12A7 shRNA Plasmid (Human) - CHH7305 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC12A7 miRNA 3'UTR clone - MiUTR1H-09439 from Creative biogene

Species Reactivities Human
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