Gene Symbol |
B3GNT6
|
Entrez Gene |
192134
|
Alt Symbol |
B3Gn-T6, BGnT-6, beta-1,3-Gn-T6, beta3Gn-T6
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
|
Other Description |
beta-1,3-N-acetylglucosaminyltransferase 6|beta-1,3-N-acetylglucosaminyltransferase protein|core 3 synthase
|
Swissprots |
Q6ZSC5 E9PKS1 Q8TAZ4 Q6ZMB0 Q8TDX1
|
Accessions |
EAW75013 Q6ZMB0 AB073740 BAB88882 AK127544 BAC87028 AK172863 BAD18819 AK292773 BAF85462 AK313682 BAG36432 BC025357 AAH25357 BC103908 AAI03909 BC103909 AAI03910 BC103910 AAI03911 CD636501 DA437068 DA439499 NM_138706 NP_619651
|
Function |
Beta-1,3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important precursor in the biosynthesis of mucin-type glycoproteins. Plays an important role in the synthesis of mucin-type O-glycans in digestive organs.
|
Subcellular Location |
Golgi apparatus membrane {ECO:0000269|PubMed:15755813}; Single-pass type II membrane protein {ECO:0000269|PubMed:15755813}.
|
Tissue Specificity |
Present in stomach and colon (at protein level). Restricted in the stomach, colon and small intestine, where core 3 structure is present. {ECO:0000269|PubMed:15755813}.
|
Top Pathways |
Mucin type O-Glycan biosynthesis
|