| Gene Symbol | B3GNT6 |
|---|---|
| Entrez Gene | 192134 |
| Alt Symbol | B3Gn-T6, BGnT-6, beta-1,3-Gn-T6, beta3Gn-T6 |
| Species | Human |
| Gene Type | protein-coding |
| Description | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 |
| Other Description | beta-1,3-N-acetylglucosaminyltransferase 6|beta-1,3-N-acetylglucosaminyltransferase protein|core 3 synthase |
| Swissprots | Q6ZSC5 E9PKS1 Q8TAZ4 Q6ZMB0 Q8TDX1 |
| Accessions | EAW75013 Q6ZMB0 AB073740 BAB88882 AK127544 BAC87028 AK172863 BAD18819 AK292773 BAF85462 AK313682 BAG36432 BC025357 AAH25357 BC103908 AAI03909 BC103909 AAI03910 BC103910 AAI03911 CD636501 DA437068 DA439499 NM_138706 NP_619651 |
| Function | Beta-1,3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important precursor in the biosynthesis of mucin-type glycoproteins. Plays an important role in the synthesis of mucin-type O-glycans in digestive organs. |
| Subcellular Location | Golgi apparatus membrane {ECO:0000269|PubMed:15755813}; Single-pass type II membrane protein {ECO:0000269|PubMed:15755813}. |
| Tissue Specificity | Present in stomach and colon (at protein level). Restricted in the stomach, colon and small intestine, where core 3 structure is present. {ECO:0000269|PubMed:15755813}. |
| Top Pathways | Mucin type O-Glycan biosynthesis |