GNAQ

Gene Symbol GNAQ
Entrez Gene 2776
Alt Symbol CMC1, G-ALPHA-q, GAQ, SWS
Species Human
Gene Type protein-coding
Description guanine nucleotide binding protein (G protein), q polypeptide
Other Description guanine nucleotide-binding protein G(q) subunit alpha|guanine nucleotide-binding protein alpha-q
Swissprots P50148 Q13462 Q9BZB9 Q6NT27 O15108 Q92471
Accessions AEV76929 AEV76930 AEV76931 CAV33030 EAW62605 EAW62606 EAW62607 EAW62608 EAW62609 EAW62610 P50148 AB073896 AF011496 AAB64301 AF329284 AAG61117 AF493896 AAM12610 AJ420425 AK055619 AK298579 BAH12817 AL832747 AM392842 CAL37720 AM393393 CAL38271 AM393764 CAL38639 BC047048 BC057777 AAH57777 BC067850 AAH67850 BC069520 AAH69520 BC075096 AAH75096 BC075097 AAH75097 CV570171 DB474490 JN184778 AEV76928 L40629 AAA99950 L76256 AAB39498 U40038 AAC50363 U43083 AAB06875 NM_002072 NP_002063
Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}. Membrane {ECO:0000250}. Nucleus membrane {ECO:0000250}. Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes. {ECO:0000250}.
Tissue Specificity Predominantly expressed in ovary, prostate, testis and colon. Down-regulated in the peripheral blood lymphocytes (PBLs) of rheumatoid arthritis patients (at protein level). {ECO:0000269|PubMed:21923740, ECO:0000269|PubMed:8664309}.
Top Pathways cGMP-PKG signaling pathway, Inflammatory mediator regulation of TRP channels, Calcium signaling pathway, Huntington's disease, Oxytocin signaling pathway

Human-GNAQ-cDNA-Clone - DC15007 from Abgent, a WuXi AppTec company

Prices $484.65
Sizes 10 µg
Species Human
Accession BC057777

Human GNAQ ORF Clone(NM_002072.3) - CDCL164901 from Creative Biomart

Species Human
Accession NM_002072.3

Human GNAQ ORF Clone (BC057777) - CDCS410592 from Creative biogene

Species Human
Accession P50148
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