GNAQ

Gene Symbol	GNAQ
Entrez Gene	2776
Alt Symbol	CMC1, G-ALPHA-q, GAQ, SWS
Species	Human
Gene Type	protein-coding
Description	guanine nucleotide binding protein (G protein), q polypeptide
Other Description	guanine nucleotide-binding protein G(q) subunit alpha|guanine nucleotide-binding protein alpha-q
Swissprots	P50148 Q13462 Q9BZB9 Q6NT27 O15108 Q92471
Accessions	AEV76929 AEV76930 AEV76931 CAV33030 EAW62605 EAW62606 EAW62607 EAW62608 EAW62609 EAW62610 P50148 AB073896 AF011496 AAB64301 AF329284 AAG61117 AF493896 AAM12610 AJ420425 AK055619 AK298579 BAH12817 AL832747 AM392842 CAL37720 AM393393 CAL38271 AM393764 CAL38639 BC047048 BC057777 AAH57777 BC067850 AAH67850 BC069520 AAH69520 BC075096 AAH75096 BC075097 AAH75097 CV570171 DB474490 JN184778 AEV76928 L40629 AAA99950 L76256 AAB39498 U40038 AAC50363 U43083 AAB06875 NM_002072 NP_002063
Function	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000250}. Membrane {ECO:0000250}. Nucleus membrane {ECO:0000250}. Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes. {ECO:0000250}.
Tissue Specificity	Predominantly expressed in ovary, prostate, testis and colon. Down-regulated in the peripheral blood lymphocytes (PBLs) of rheumatoid arthritis patients (at protein level). {ECO:0000269|PubMed:21923740, ECO:0000269|PubMed:8664309}.
Top Pathways	cGMP-PKG signaling pathway, Inflammatory mediator regulation of TRP channels, Calcium signaling pathway, Huntington's disease, Oxytocin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human G protein alpha q/11 peptide - ab86404 from Abcam Category Peptide

Human GNAQ full length protein - ab132889 from Abcam Category Protein Source Wheat germ Species Human

Human GNAQ full length protein - ab176627 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human GNAQ protein fragment - ab158539 from Abcam Category Protein Source Wheat germ Species Human

Human Histamine H2 Receptor - Gq&alpha: fusion full length protein - ab90397 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

GNAQ Antibody Blocking Peptide - LS-E3045 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GNAQ Antibody Blocking Peptide - LS-E19687 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GNAQ Antibody Blocking Peptide - LS-E19686 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GNAQ Antibody Blocking Peptide - LS-E27616 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human GNAQ Protein - H00002776-P01 from Novus Biologicals Category Protein Prices $529.00 Sizes 25 µg Source Wheat Germ Species Human

GNAQ Partial Recombinant Protein - H00002776-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

GNAQ-Antibody-N-term-Blocking-Peptide - BP14179a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GNAQ Immunizing peptide - orb66140 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

GNAQ Blocking Peptide - 33R-2030 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GNAQ Peptide - AC21-2434-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

G protein alpha Q / GNAQ (1-359, His-tag) - AR51618PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

G protein alpha Q / GNAQ (1-359, His-tag) - AR51618PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

G protein alpha Q / GNAQ - H00002776-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

G protein alpha Q / GNAQ - H00002776-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

G protein alpha Q / GNAQ - H00002776-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

G protein alpha Q / GNAQ - H00002776-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GNAQ Peptide - 42-414P from ProSci Category Peptide Species Human, Mouse, Rat

GNAQ fusion protein - Ag4947 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human GNAQ, His-tagged - GNAQ-8728H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human GNAQ, GST-tagged - GNAQ-13350H from Creative Biomart Category Protein Source E.coli Species Human

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