| Gene Symbol |
ZNF750
|
| Entrez Gene |
79755
|
| Alt Symbol |
ZFP750
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc finger protein 750
|
| Other Description |
protein ZNF750
|
| Swissprots |
Q9H899 Q32MQ0
|
| Accessions |
EAW89824 Q32MQ0 AI539029 AK023903 BAB14718 AK301690 BAG63162 BC109036 AAI09037 BC109037 AAI09038 CO245511 DA433713 DA872185 NM_024702 NP_078978
|
| Function |
Transcription factor involved in epidermis differentiation. Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late epidermal differentiation genes. Specifically binds to the promoter of KLF4 and promotes its expression. {ECO:0000269|PubMed:22364861}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:22364861}.
|
| Tissue Specificity |
Expressed in the skin, prostate, lung, placenta and thymus, and at low level in T-cells. Not expressed in peripheral blood leukocytes, pancreas and brain. Clearly expressed in primary keratinocytes but not in fibroblasts. {ECO:0000269|PubMed:16751772}.
|