Gene Symbol | ZNF750 |
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Entrez Gene | 79755 |
Alt Symbol | ZFP750 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger protein 750 |
Other Description | protein ZNF750 |
Swissprots | Q9H899 Q32MQ0 |
Accessions | EAW89824 Q32MQ0 AI539029 AK023903 BAB14718 AK301690 BAG63162 BC109036 AAI09037 BC109037 AAI09038 CO245511 DA433713 DA872185 NM_024702 NP_078978 |
Function | Transcription factor involved in epidermis differentiation. Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late epidermal differentiation genes. Specifically binds to the promoter of KLF4 and promotes its expression. {ECO:0000269|PubMed:22364861}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:22364861}. |
Tissue Specificity | Expressed in the skin, prostate, lung, placenta and thymus, and at low level in T-cells. Not expressed in peripheral blood leukocytes, pancreas and brain. Clearly expressed in primary keratinocytes but not in fibroblasts. {ECO:0000269|PubMed:16751772}. |
ZNF750 CRISPR/Cas9 KO Plasmid (h) - sc-408278 from Santa Cruz Biotechnology
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ZNF750 HDR Plasmid (h) - sc-408278-HDR from Santa Cruz Biotechnology
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ZNF750 Double Nickase Plasmid (h) - sc-408278-NIC from Santa Cruz Biotechnology
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ZNF750 Double Nickase Plasmid (h2) - sc-408278-NIC-2 from Santa Cruz Biotechnology
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ZNF750 CRISPR Activation Plasmid (h) - sc-408278-ACT from Santa Cruz Biotechnology
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ZNF750 CRISPR Activation Plasmid (h2) - sc-408278-ACT-2 from Santa Cruz Biotechnology
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ZNF750 Lentiviral Activation Particles (h) - sc-408278-LAC from Santa Cruz Biotechnology
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ZNF750 Lentiviral Activation Particles (h2) - sc-408278-LAC-2 from Santa Cruz Biotechnology
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ZNF750 siRNA (h) - sc-93787 from Santa Cruz Biotechnology
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ZNF750 shRNA Plasmid (h) - sc-93787-SH from Santa Cruz Biotechnology
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ZNF750 shRNA (h) Lentiviral Particles - sc-93787-V from Santa Cruz Biotechnology
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ZNF750 RNAi - H00079755-R01 from Novus Biologicals
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MISSION® esiRNA - EHU044441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23687 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23687 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06068 from Sigma-Aldrich
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ZNF750 siRNA (Human) - CRJ2543 from Cohesion Biosciences
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ZNF750 - MBS8219135 from MyBioSource
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shRNA set against Human ZNF750 (NM_024702.2) - SHH455180 from Creative biogene
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ZNF750 shRNA Plasmid (Human) - CHJ2543 from Cohesion Biosciences
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ZNF750 miRNA 3'UTR clone - MiUTR1H-11717 from Creative biogene
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