PPP2R2B

Gene Symbol	PPP2R2B
Entrez Gene	5521
Alt Symbol	B55BETA, PP2AB55BETA, PP2ABBETA, PP2APR55B, PP2APR55BETA, PR2AB55BETA, PR2ABBETA, PR2APR55BETA, PR52B, PR55-BETA, PR55BETA, SCA12
Species	Human
Gene Type	protein-coding
Description	protein phosphatase 2, regulatory subunit B, beta
Other Description	PP2A subunit B isoform B55-beta|PP2A subunit B isoform PR55-beta|PP2A subunit B isoform R2-beta|PP2A, subunit B, B-beta isoform|protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform|protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform|serine/threonine protein phosphatase 2A, 55 kDa regulatory subunit B, beta isoform|serine/threonine protein phosphatase 2A, neuronal isoform|serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
Swissprots	D3DQF8 B7Z304 D3DQF7 A6NEJ2 A8K102 Q00005 B7Z2F2 B3KPD0 G3V149
Accessions	AAF74024 EAW61829 EAW61830 EAW61831 EAW61832 EAW61833 EAW61834 EAW61835 Q00005 AI621232 AK056192 BAG51642 AK289717 BAF82406 AK294659 BAH11838 AK295347 BAH12040 AK314810 AL540315 AV726282 BC031790 AAH31790 BI669304 BP195204 BX464346 BX647887 DA155307 DA158596 DA365141 DA522334 DA523686 DA533318 DQ891785 ABM82711 DQ894969 ABM85895 M64930 AAA36491 NM_001271899 NP_001258828 NM_001271900 NP_001258829 NM_001271948 NP_001258877 NM_181674 NP_858060 NM_181675 NP_858061 NM_181676 NP_858062 NM_181677 NP_858063 NM_181678 NP_858064 NR_073526 NR_073527
Function	The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity). {ECO:0000250}.
Subcellular Location	Isoform 1: Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Membrane {ECO:0000250}.
Tissue Specificity	Brain.
Top Pathways	Dopaminergic synapse, mRNA surveillance pathway, PI3K-Akt signaling pathway, Hepatitis C, Hippo signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PPP2R2B-Over-expression-Lysate - LY11500a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

PPP2R2B overexpression lysate - LY405663 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PPP2R2B overexpression lysate - LY405664 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PPP2R2B overexpression lysate - LY405665 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

PPP2R2B overexpression lysate - LY405666 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

PPP2R2B overexpression lysate - LY405667 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

PPP2R2B overexpression lysate - LY430556 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PPP2R2B 293 Cell Lysate - 403678 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

PPP2R2B Overexpression Lysate (Native) - NBL1-14695 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PPP2R2B Overexpression Lysate (Native) - NBP2-07854 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

PP2A-B55-β (h): 293T Lysate - sc-175592 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

PPP2R2B Over-expression Lysate Product - GWB-32709E from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

PPP2R2B Overexpression Lysate (Native) - NBP2-09803 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PPP2R2B Overexpression Lysate (Native) - NBP2-04901 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PPP2R2B Overexpression Lysate (Native) - NBP2-09442 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PPP2R2B Overexpression Lysate (Native) - NBP2-10047 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PPP2R2B Overexpression Lysate (Denatured) - H00005521-T02 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human PPP2R2B Knockdown Stable Cell Line - CSC-DC012273 from Creative biogene Category Cell Line Species Human

Human PPP2R2B Knockout Cell Line-HeLa - CSC-RT1352 from Creative biogene Category Cell Line Species Human

PPP2R2B KO Cell Lysate-HeLa - CLKO-1204 from Creative biogene Category Cell Lysate

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