PPP2R2B

Gene Symbol PPP2R2B
Entrez Gene 5521
Alt Symbol B55BETA, PP2AB55BETA, PP2ABBETA, PP2APR55B, PP2APR55BETA, PR2AB55BETA, PR2ABBETA, PR2APR55BETA, PR52B, PR55-BETA, PR55BETA, SCA12
Species Human
Gene Type protein-coding
Description protein phosphatase 2, regulatory subunit B, beta
Other Description PP2A subunit B isoform B55-beta|PP2A subunit B isoform PR55-beta|PP2A subunit B isoform R2-beta|PP2A, subunit B, B-beta isoform|protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform|protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform|serine/threonine protein phosphatase 2A, 55 kDa regulatory subunit B, beta isoform|serine/threonine protein phosphatase 2A, neuronal isoform|serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
Swissprots D3DQF8 B7Z304 D3DQF7 A6NEJ2 A8K102 Q00005 B7Z2F2 B3KPD0 G3V149
Accessions AAF74024 EAW61829 EAW61830 EAW61831 EAW61832 EAW61833 EAW61834 EAW61835 Q00005 AI621232 AK056192 BAG51642 AK289717 BAF82406 AK294659 BAH11838 AK295347 BAH12040 AK314810 AL540315 AV726282 BC031790 AAH31790 BI669304 BP195204 BX464346 BX647887 DA155307 DA158596 DA365141 DA522334 DA523686 DA533318 DQ891785 ABM82711 DQ894969 ABM85895 M64930 AAA36491 NM_001271899 NP_001258828 NM_001271900 NP_001258829 NM_001271948 NP_001258877 NM_181674 NP_858060 NM_181675 NP_858061 NM_181676 NP_858062 NM_181677 NP_858063 NM_181678 NP_858064 NR_073526 NR_073527
Function The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity). {ECO:0000250}.
Subcellular Location Isoform 1: Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Membrane {ECO:0000250}.
Tissue Specificity Brain.
Top Pathways Dopaminergic synapse, mRNA surveillance pathway, PI3K-Akt signaling pathway, Hepatitis C, Hippo signaling pathway

Human-PPP2R2B-cDNA-Clone - DC06296 from Abgent, a WuXi AppTec company

Prices $598.05
Sizes 10 µg
Species Human
Accession BC031790

PPP2R2B - MBS1278095 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC031790

Human PPP2R2B cDNA clone(NM_001127381.1) - CDFH014932 from Creative Biomart

Species Human
Accession NM_001127381.1

Human PPP2R2B cDNA clone(NM_004576.2) - CDFH014933 from Creative Biomart

Species Human
Accession NM_004576.2

Human PPP2R2B ORF Clone(NM_004576.2) - CDCR288371 from Creative Biomart

Species Human
Accession NM_004576.2

Human PPP2R2B ORF Clone(NM_004576.2) - CDCR288372 from Creative Biomart

Species Human
Accession NM_004576.2

Human PPP2R2B ORF Clone(NM_001127381.1) - CDCR348643 from Creative Biomart

Species Human
Accession NM_001127381.1

Human PPP2R2B ORF Clone(NM_001127381.1) - CDCR348644 from Creative Biomart

Species Human
Accession NM_001127381.1

Human PPP2R2B ORF Clone(NM_004576.2) - CDCR288371 from Creative biogene

Species Human

Human PPP2R2B ORF Clone(NM_001127381.1) - CDCR348643 from Creative biogene

Species Human

human PPP2R2B ORF clone (NM_181676.2) - CDCH066984 from Creative biogene

Species Human

human PPP2R2B ORF clone (NM_181678.2) - CDCH066986 from Creative biogene

Species Human

Human PPP2R2B ORF Clone (BC031790) - CDCS407795 from Creative biogene

Species Human
Accession Q00005

Human PPP2R2B cDNA Clone(NM_001127381.1) - CDFH014932 from Creative biogene

Species Human

Human PPP2R2B cDNA Clone(NM_004576.2) - CDFH014933 from Creative biogene

Species Human
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