IRS1

Gene Symbol	IRS1
Entrez Gene	3667
Alt Symbol	HIRS-1
Species	Human
Gene Type	protein-coding
Description	insulin receptor substrate 1
Other Description	IRS-1
Swissprots	P35568
Accessions	AAB21608 AGG19175 AGG19176 AGG19177 AHG12642 AHG12643 AHG12644 CAD79961 CBL64020 EAW70838 EAW70839 P35568 AW469017 BC053895 AAH53895 EU831611 ACE87211 EU831698 ACE86532 S62539 AAB27175 NM_005544 NP_005535
Function	May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity). {ECO:0000250}.
Top Pathways	AMPK signaling pathway, cGMP-PKG signaling pathway, Non-alcoholic fatty liver disease (NAFLD), MicroRNAs in cancer, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PathScan ® Phospho-IRS-1 (Ser302) Sandwich ELISA Antibody Pair - 7284 from Cell Signaling Technology Category Antibody Pair Prices $459.00 Sizes 1 kit (Reagents for 4 x 96 well plates)

PathScan ® Phospho-IRS-1 (Ser307) Sandwich ELISA Kit - 7287 from Cell Signaling Technology Category ELISA Kit Prices $489.00 Sizes 1 kit (96 assays)

PathScan ® Phospho-IRS-1 (Ser612) Sandwich ELISA Kit - 7332 from Cell Signaling Technology Category ELISA Kit Prices $489.00 Sizes 1 kit (96 assays)

PathScan ® Phospho-IRS-1 (panTyr) Sandwich ELISA Antibody Pair - 7347 from Cell Signaling Technology Category Antibody Pair Prices $459.00 Sizes 1 kit (Reagents for 4 x 96 well plates)

PathScan ® Phospho-IRS-1 (panTyr) Sandwich ELISA Kit - 7133 from Cell Signaling Technology Category ELISA Kit Prices $489.00 Sizes 1 kit (96 assays)

PathScan ® Total IRS-1 Sandwich ELISA Kit - 7328 from Cell Signaling Technology Category ELISA Kit Prices $489.00 Sizes 1 kit (96 assays)

PathScan® Phospho-IRS-1 (Ser612) Sandwich ELISA Kit - 7213 from Cell Signaling Technology Category ELISA Kit

PathScan ® Phospho-IRS-1 (Ser302) Sandwich ELISA Kit - 7283 from Cell Signaling Technology Category ELISA Kit

PathScan ® Phospho-IRS-1 (Ser307) Sandwich ELISA Antibody Pair - 7288 from Cell Signaling Technology Category Antibody Pair

PathScan® Total IRS-1 Sandwich ELISA Kit - 7214 from Cell Signaling Technology Category ELISA Kit

Mouse/Human/Rat Phospho-IRS1 (Ser1101) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1148 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.312-20 ng/ml

Mouse/Human/Rat Phospho-IRS1 (Ser612) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1149 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.312-20 ng/ml

Mouse/Human/Rat Phospho-IRS1 (Ser307) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1110 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.312-20 ng/ml

Mouse/Human/Rat Phospho-IRS1 (Tyr896) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1708 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.312-20 ng/ml

Mouse/Human/Rat IRS1 ELISA Kit (Cell-Based ELISA) - LS-F2088 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.312-20 ng/ml

Mouse/Human/Rat Phospho-IRS1 (Ser323) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1178 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.312-20 ng/ml

Mouse/Human/Rat Phospho-IRS1 (Ser312) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1540 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.312-20 ng/ml

Mouse/Human/Rat Phospho-IRS1 (Ser636) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1541 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.312-20 ng/ml

Mouse IRS1 ELISA Kit (Sandwich ELISA) - LS-F8571 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.128 ng/ml Range 0.312-20 ng/ml

Rat IRS1 ELISA Kit (Sandwich ELISA) - LS-F11840 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 0.312-20 ng/ml

Human Insulin Receptor Substrate 1 ELISA Kit - abx055140 from Abbexa Category ELISA Kit

Insulin receptor substrate 1, Human, ELISA Kit - E01I0403 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Insulin receptor substrate 1, IRS1, Human, ELISA Kit - E1660h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Insulin Receptor Substrate 1, ELISA Kit - MBS039684 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 10pg/ml Range 62.5pg/ml-2000pg/ml

Insulin Receptor Substrate 1, ELISA Kit - MBS023815 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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