RAD18

Gene Symbol RAD18
Entrez Gene 56852
Alt Symbol RNF73
Species Human
Gene Type protein-coding
Description RAD18 E3 ubiquitin protein ligase
Other Description E3 ubiquitin-protein ligase RAD18|RAD18 homolog|RAD18, S. cerevisiae, homolog|RING finger protein 73|hHR18|hRAD18|postreplication repair protein RAD18|postreplication repair protein hRAD18p
Swissprots Q9NRT6 Q58F55 Q9NS91
Accessions AAX44049 EAW63948 EAW63949 Q9NS91 AB035274 BAA99284 AF169796 AAF80856 AK023075 BAB14392 AK123966 AK222771 BAD96491 AY004333 AAF86618 BC001302 AAH01302 DQ891197 ABM82123 DQ894380 ABM85306 DW433240 NM_020165 NP_064550
Function E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap- filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono- ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity. {ECO:0000269|PubMed:17108083, ECO:0000269|PubMed:21659603}.
Subcellular Location Nucleus {ECO:0000250}.

Rad18 CRISPR/Cas9 KO Plasmid (h) - sc-406099 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rad18 HDR Plasmid (h) - sc-406099-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rad18 Double Nickase Plasmid (h) - sc-406099-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rad18 Double Nickase Plasmid (h2) - sc-406099-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rad18 CRISPR Activation Plasmid (h) - sc-406099-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rad18 CRISPR Activation Plasmid (h2) - sc-406099-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rad18 Lentiviral Activation Particles (h) - sc-406099-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rad18 Lentiviral Activation Particles (h2) - sc-406099-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rad18 siRNA (h) - sc-72142 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Rad18 shRNA Plasmid (h) - sc-72142-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Rad18 shRNA (h) Lentiviral Particles - sc-72142-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RAD18 RNAi - H00056852-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: RAD18 RNAi [H00056852-R01V] - Analysis of RAD18 over-expressed 293 cell line, cotransfected with RAD18 Validated Chimera RNAi or non-transfected control. Blot probed with H00056852-M01. GAPDH (36.1 kDa) used as loading control.

RAD18 RNAi - H00056852-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU013431 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK1918 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1919 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1920 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN17892 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17892 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09483 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09483

RAD18 siRNA (Human) - CRJ1189 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RAD18 - MBS8240957 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RAD18 (NM_020165.3) - SHH388904 from Creative biogene

Category siRNA
Species Reactivities Human

Rad18 CRISPR/Cas9 KO Plasmid (h2) - sc-406099-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rad18 HDR Plasmid (h2) - sc-406099-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human
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