ATP2A3

Gene Symbol ATP2A3
Entrez Gene 489
Alt Symbol SERCA3
Species Human
Gene Type protein-coding
Description ATPase, Ca++ transporting, ubiquitous
Other Description ATPase, Ca(2+)-transporting, ubiquitous|SR Ca(2+)-ATPase 3|adenosine triphosphatase, calcium|calcium pump 3|calcium-translocating P-type ATPase|sarco/endoplasmic reticulum Ca2+ -ATPase|sarcoplasmic/endoplasmic reticulum calcium ATPase 3
Swissprots O75501 O60901 Q16115 Q8TEX6 A8MZG0 D3DTJ8 Q93084 Q6JHX1 O60900 O75502 Q8TEX5
Accessions CAA75739 CAA75747 CAA75748 CAA93736 CDM55639 CDM55640 CDM55641 CDM55642 CDM55643 CDM55644 EAW90460 EAW90461 EAW90462 EAW90463 EAW90464 EAW90465 EAW90466 EAW90467 EAW90468 EAW90469 EAW90470 Q93084 AA643105 AF068220 AAC24525 AF068221 AAC24526 AF458228 AAL78967 AF458229 AAL78968 AK292716 BAF85405 AY460339 AAR15415 BC035729 AAH35729 DQ893317 ABM84243 EU176809 ABW03610 S68239 AAB29700 Z69881 CAA93737 XM_005256656 XP_005256713 XM_011523881 XP_011522183 XM_011523882 XP_011522184 XM_011523883 XP_011522185 XM_011523884 XP_011522186 XM_011523885 XP_011522187 XM_011523886 XP_011522188 XM_011523887 XP_011522189 XM_011523888 XP_011522190 XM_011523889 XP_011522191 XM_011523890 XP_011522192 XM_011523891 XP_011522193 XM_011523892 XP_011522194 NM_005173 NP_005164 NM_174953 NP_777613 NM_174954 NP_777614 NM_174955 NP_777615 NM_174956 NP_777616 NM_174957 NP_777617 NM_174958 NP_777618
Function This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. {ECO:0000269|PubMed:11956212, ECO:0000269|PubMed:15028735}.
Subcellular Location Nucleus membrane {ECO:0000269|PubMed:15028735}; Multi-pass membrane protein {ECO:0000269|PubMed:15028735}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:15028735}; Multi-pass membrane protein {ECO:0000269|PubMed:15028735}. Sarcoplasmic reticulum membrane {ECO:0000269|PubMed:15028735}; Multi-pass membrane protein {ECO:0000269|PubMed:15028735}.
Tissue Specificity Found in most tissues. Most abundant in thymus, trachea, salivary gland, spleen, bone marrow, lymph node, peripheral leukocytes, pancreas and colon. Also detected in fetal tissues. Expressed in cell lineages of hematopoietic, epithelial, or embryonic origin and also expressed in several cancer cell lines. {ECO:0000269|PubMed:11956212, ECO:0000269|PubMed:15028735}.
Top Pathways Alzheimer's disease, Calcium signaling pathway, Pancreatic secretion, cGMP-PKG signaling pathway

SERCA3 (N-19) - sc-8097 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SERCA3 (N-19): sc-8097. Western blot analysis of SERCA3 expression in human platelet extract.

SERCA3 (G-16) - sc-26509 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SERCA3 (V-19) - sc-26508 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SERCA3 (F-15) - sc-26507 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SERCA3 (L-16) - sc-26510 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SERCA3 (PL/IM430) - sc-81759 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SERCA3 (PL/IM430): sc-81759. Western blot analysis of SERCA3 expression in human platelet extract.

Anti-SERCA3 ATPase antibody - ab54876 from Abcam

Prices $380.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Overlay histogram showing Jurkat cells stained with ab54876 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab54876, 0.1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG2a [ICIGG2A] (ab91361, 0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-SERCA3 ATPase antibody - ab3339 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SERCA3 ATPase antibody - ab85753 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SERCA3 ATPase antibody (ab85753) at 1 µg/ml (5% skim milk / PBS buffer) + Jurkat cell lysate at 10 µgSecondaryanti-Rabbit IgG HRP at 1/50000 dilution

Anti-SERCA3 ATPase antibody [2H3] - ab124376 from Abcam

Prices $464.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2H3
ab124376, at 5 µg/ml, staining SERCA3 ATPase in formalin fixed, paraffin embedded Human Brain Cerebellum tissue by Immunohistochemistry.

Anti-ATP2A3 / SERCA3 Antibody (aa29-39) - LS-C74404 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ATP2A3 / SERCA3 Antibody (aa828-877) - LS-C102236 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ATP2A3 / SERCA3 antibody LS-C102236 Western blot of Jurkat lysate.

Anti-ATP2A3 / SERCA3 Antibody (clone 2H3) IHC-plus™ - LS-B6010 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2H3
Anti-ATP2A3 / SERCA3 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6010 concentration 5 ug/ml.

SERCA3 ATPase Antibody - NBP2-20306 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SERCA3 ATPase Antibody [NBP2-20306] - Sample (30 ug of whole cell lysate) A: Jurkat B: Raji C: K562 5% SDS PAGE gel, diluted at 1:2000.

SERCA3 ATPase Antibody (2H3) - H00000489-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2H3
Western Blot: SERCA3 ATPase Antibody (2H3) [H00000489-M01] - ATP2A3 monoclonal antibody (M01), clone 2H3 Analysis of ATP2A3 expression in HL-60.

SERCA3 ATPase Antibody - NBP1-87054 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: SERCA3 ATPase Antibody [NBP1-87054] - Immunohistochemical staining of human cerebellum shows strong nucleolar and cytoplasmic positivity in purkinje cells.

Anti-ATP2A3 antibody produced in rabbit - SAB2100181 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ATP2A3: <B>Cat. No.SAB2100181</B>: ATP2A3 in Jurkat cell lysate with ATP2A3 antibody at 1.0 μg/mL.

Monoclonal Anti-ATP2A3 antibody produced in mouse - WH0000489M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2H3
<B>Immunoblotting</B><BR/>Monoclonal Anti-ATP2A3, <B>Cat. No. WH0000489M1</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~113.9 kDa using HL-60 lysate.

Anti-SERCa3 ATPase antibody produced in rabbit - S1564 from Sigma-Aldrich

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Monoclonal Anti-ATP2A3 antibody produced in mouse - SAB1403588 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B9
<B>Immunoblotting</B><BR/>Monoclonal Anti-ATP2A3: <B>Cat. No. SAB1403588</B>: Antibody concentration: 1 μg/mL. Specific band of ~39.3 kDa using immunogen protein lysate.

Anti-ATP2A3 antibody produced in rabbit - HPA007180 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ATP2A3: <B>Cat. No. HPA007180</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human cerebellum shows strong nucleolar and cytoplasmic positivity in purkinje cells.

Monoclonal Anti-SERCA3 antibody produced in mouse - S7199 from Sigma-Aldrich

Prices $61.10, $336.00
Sizes 25 µl, 200 µl
Host Mouse
Clonality Monoclonal
Clone PL/IM430

ATP2A3 Antibody (OALA05346) - OALA05346 from Aviva Systems Biology

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone [clone 2H3]

ATP2A3 antibody - middle region (ARP46580_P050) - ARP46580_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATP2A3-Antibody-monoclonal-M01 - AT1234a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2H3
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (38.94 KDa) .
Search more