CD8A

Gene Symbol CD8A
Entrez Gene 925
Alt Symbol CD8, Leu2, MAL, p32
Species Human
Gene Type protein-coding
Description CD8a molecule
Other Description CD8 antigen, alpha polypeptide (p32)|Leu2 T-lymphocyte antigen|OKT8 T-cell antigen|T cell co-receptor|T-cell antigen Leu2|T-cell surface glycoprotein CD8 alpha chain|T-lymphocyte differentiation antigen T8/Leu-2|T8 T-cell antigen
Swissprots P01732 B4DT80 Q13970 Q4ZG17 D6W5M8
Accessions AAA59674 AAA79217 AAA79218 AAX88864 EAW99438 EAW99439 EAW99440 EAW99441 P01732 AA668685 AK097942 BAG53555 AK124156 BAC85789 AK300089 BAG61892 AY039664 AAK72403 BC025715 AAH25715 DA075688 DB129686 DQ893323 ABM84249 DQ896638 ABM87637 DQ896639 ABM87638 M12824 AAA61133 M12828 AAB04637 NM_001145873 NP_001139345 NM_001768 NP_001759 NM_171827 NP_741969 NR_027353
Function Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
Subcellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein.
Top Pathways Hematopoietic cell lineage, T cell receptor signaling pathway, Cell adhesion molecules (CAMs), Primary immunodeficiency, Antigen processing and presentation

CD8 (RIV11) Mouse mAb - 3572 from Cell Signaling Technology

Prices $239.00
Sizes 400 µl (100 tests)
Host Mouse
Clonality Monoclonal
Clone RIV11
Flow cytometric analysis of peripheral blood using CD8 (RIV11) Mouse mAb.

CD8 (MCD8) - sc-51735 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
CD8 (MCD8): sc-51735. Indirect FCM analysis of human peripheral blood leukocytes stained with CD8 (MCD8), followed by PE-conjugated goat anti-mouse IgG<sub>1</sub>: sc-3764. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-3877.

CD8 (5H10-1) - sc-53675 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rat
Clonality Monoclonal

CD8 (5F10) - sc-70794 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

CD8-α (C-19) - sc-1141 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CD8-α (C-19): sc-1141. Western blot analysis of CD8-α expression in CCRF-CEM whole cell lysate.

CD8-α (C8/144B) - sc-53212 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD8-α (C8/144B): sc-53212. Western blot analysis of CD8-α expression in human PBL whole cell lysate.

CD8-α (H-160) - sc-7188 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CD8-α (H-160): sc-7188. Western blot analysis of CD8-α expression in mouse PBL whole cell lysate.

CD8-α (D-9) - sc-7970 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD8-α (D-9): sc-7970. Western blot analysis of CD8-α expression in CCRF-CEM (A) and MOLT-4 (B) whole cell lysates.

CD8-α (0.N.66) - sc-70791 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD8-α (0.N.66): sc-70791. Western blot analysis of CD8-α expression in SUP-T1 whole cell lysate.

Anti-CD38 + CD8 antibody [FS02 + 733] (Dual color: FITC + PE) - ab1239 from Abcam

Prices $216.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone FS02 + 733

Anti-CD8 + HLA Class II antibody [733 + LN3] (Dual color: FITC + PE) - ab1236 from Abcam

Prices $216.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 733 + LN3

Anti-CD8 alpha antibody - ab187366 from Abcam

Prices $373.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal

Anti-CD8 alpha antibody - ab108166 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CD8 alpha antibody (ab108166) at 0.25 µg/ml + Humn fetal lung lysate at 10 µg

Anti-CD8 alpha antibody - ab171773 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD8 alpha antibody (ab171773) at 1 µg/mlLane 1 : CD8 alpha-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Rabbit IgG (H+L), Peroxidase Conjugated secondary antibody at 1/7500 dilution

Anti-CD8 alpha antibody [C8/468] - ab187279 from Abcam

Prices $379.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone C8/468
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human tonsil tissue (10X) labeling CD8 alpha with ab187279 at 1/100 dilution for 30 minutes at RT.

Anti-CD8 alpha antibody [C8/468 + C8/144B] - ab199016 from Abcam

Prices $379.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone C8/468 + C8/144B
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human tonsil tissue labeling CD8 alpha with ab199016 at 1 µg/ml for 30 minutes at RT.

Anti-CD8 alpha antibody [EP1150] - ab108343 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1150
All lanes : Anti-CD8 alpha antibody [EP1150] (ab108343) at 1/1000 dilutionLane 1 : MOLT-4 cell lysates Lane 2 : Jurkat cell lysates SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-CD8 alpha antibody [EPR10640(2)] - N-terminal - ab189926 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10640(2)
Immunohistochemical analysis of paraffin-embedded, Human tonsil tissue tissue labeling CD8 alpha with ab189926 at a 1/500 dilution. Counter stained with hematoxylin. Negative control also shown.

Anti-CD8 alpha antibody [EPR1148(2)] - ab108292 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR1148(2)
All lanes : Anti-CD8 alpha antibody [EPR1148(2)] (ab108292) at 1/1000 dilutionLane 1 : MOLT-4 lysateLane 2 : Jurkat lysateLane 3 : THP-1 lysateLane 4 : Human thymus lysateLysates/proteins at 10 µg per lane.

Anti-CD8 alpha antibody [HIT8a] - ab95594 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone HIT8a

Anti-CD8 alpha antibody [HIT8a] (Biotin) - ab95592 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone HIT8a
ab95592 at 0.5 µg per test staining CD8 alpha in normal human peripheral blood cells followed by Streptavidin PE by Flow Cytometry. Cells in the lymphocyte gate were used for analysis.

Anti-CD8 alpha antibody [HIT8a] (FITC) - ab95591 from Abcam

Prices $188.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone HIT8a
ab95591 at 20 µl (0.5 µg)/per test staining normal human peripheral blood cells (filled histogram) by Flow Cytometry. Mouse IgG1 ? Isotype Control FITC is shown in the open histogram. Cells in the lymphocyte gate were used for analysis.

Anti-CD8 alpha antibody [HIT8a] - Low endotoxin, Azide free - ab185771 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone HIT8a

Anti-CD8 alpha antibody [RPA-T8] - ab95593 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone RPA-T8
ab95593 at 1 µg per test, followed by Anti-Mouse IgG FITC, staining CD8 alpha in Human peripheral blood lymphocytes.

Anti-CD8 alpha antibody [RPA-T8] (Allophycocyanin) - ab86892 from Abcam

Prices $376.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone RPA-T8
ab86892 staining CD8 alpha in cynomolgus monkey whole blood cells by Flow Cytometry. Red blood cells were lysed. The sample was incubated with the primary antibody (1/100 in PBS + 0.5% BSA) for 1 hour at 4°C.Gating Strategy: Live Cells.See Abreview
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