CD8A

Gene Symbol	CD8A
Entrez Gene	925
Alt Symbol	CD8, Leu2, MAL, p32
Species	Human
Gene Type	protein-coding
Description	CD8a molecule
Other Description	CD8 antigen, alpha polypeptide (p32)|Leu2 T-lymphocyte antigen|OKT8 T-cell antigen|T cell co-receptor|T-cell antigen Leu2|T-cell surface glycoprotein CD8 alpha chain|T-lymphocyte differentiation antigen T8/Leu-2|T8 T-cell antigen
Swissprots	P01732 B4DT80 Q13970 Q4ZG17 D6W5M8
Accessions	AAA59674 AAA79217 AAA79218 AAX88864 EAW99438 EAW99439 EAW99440 EAW99441 P01732 AA668685 AK097942 BAG53555 AK124156 BAC85789 AK300089 BAG61892 AY039664 AAK72403 BC025715 AAH25715 DA075688 DB129686 DQ893323 ABM84249 DQ896638 ABM87637 DQ896639 ABM87638 M12824 AAA61133 M12828 AAB04637 NM_001145873 NP_001139345 NM_001768 NP_001759 NM_171827 NP_741969 NR_027353
Function	Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
Subcellular Location	Isoform 1: Cell membrane; Single-pass type I membrane protein.
Top Pathways	Hematopoietic cell lineage, T cell receptor signaling pathway, Cell adhesion molecules (CAMs), Primary immunodeficiency, Antigen processing and presentation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CD8-α CRISPR/Cas9 KO Plasmid (h) - sc-400372 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CD8-α HDR Plasmid (h) - sc-400372-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CD8-α Double Nickase Plasmid (h) - sc-400372-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CD8-α Double Nickase Plasmid (h2) - sc-400372-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CD8-α CRISPR Activation Plasmid (h) - sc-400372-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CD8-α CRISPR Activation Plasmid (h2) - sc-400372-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CD8-α Lentiviral Activation Particles (h) - sc-400372-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CD8-α Lentiviral Activation Particles (h2) - sc-400372-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CD8-α siRNA (h) - sc-29247 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CD8-α shRNA Plasmid (h) - sc-29247-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CD8-α shRNA (h) Lentiviral Particles - sc-29247-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CD8-α siRNA (h2) - sc-35028 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CD8-α shRNA Plasmid (h2) - sc-35028-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CD8-α shRNA (h2) Lentiviral Particles - sc-35028-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CD8-α siRNA (h2) - sc-43676 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CD8-α shRNA Plasmid (h2) - sc-43676-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CD8-α shRNA (h2) Lentiviral Particles - sc-43676-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CD8 alpha RNAi - H00000925-R04 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

CD8 alpha RNAi - H00000925-R03 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU067981 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1119 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit - CKOZFN1118 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1118 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1119 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12551 from Sigma-Aldrich Category miRNA

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