MPG

Gene Symbol MPG
Entrez Gene 4350
Alt Symbol AAG, ADPG, APNG, CRA36.1, MDG, Mid1, PIG11, PIG16, anpg
Species Human
Gene Type protein-coding
Description N-methylpurine-DNA glycosylase
Other Description 3' end of the Mid1 gene, localized 68 kb upstream the humanzeta globin gene on 16p|3-alkyladenine DNA glycosylase|3-methyladenine DNA glycosidase|CRA36.1 (3-methyl-adenine DNA glycosylase)|DNA-3-methyladenine glycosylase|N-methylpurine-DNA glycosylase, MPG|proliferation-inducing protein 11|proliferation-inducing protein 16
Swissprots G5E9E2 Q9NNX5 Q15961 Q96S33 Q15275 Q96BZ6 P29372 Q13770 Q5J9I4
Accessions AAB58462 AAK61213 AAM14628 ABD95906 CAA93540 CAI95610 CAM26663 EAW85870 EAW85871 EAW85872 P29372 AK308654 AL520052 AW083039 AY258284 AAP82229 BC014991 AAH14991 BG823448 BM796301 DQ895912 ABM86838 L10752 AAF77073 M71215 AAA58369 M74905 AAA58627 M99626 AAB46421 S51033 AAB19537 X56528 CAA39875 NM_001015052 NP_001015052 NM_001015054 NP_001015054 NM_002434 NP_002425
Function Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:23290262}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000269|PubMed:23290262}. Nucleus {ECO:0000269|PubMed:23290262}.
Top Pathways Base excision repair

APNG (D-2) - sc-390684 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
APNG (D-2): sc-390684. Western blot analysis of APNG expression in HeLa nuclear extract (A) and Caki-1 whole cell lysate (B).

APNG (C-19) - sc-21446 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

APNG (H-232) - sc-292808 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
APNG (H-232): sc-292808. Western blot analysis of APNG expression in HeLa (A) and Jurkat (B) whole cell lysates.

APNG (3D1) - sc-101237 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
APNG (3D1): sc-101237. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing nuclear localization.

Anti-MPG antibody - ab55461 from Abcam

Prices $390.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
MPG antibody (ab55461) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human kidney.

Anti-MPG antibody - ab196553 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MPG antibody (ab196553) at 1/500 dilutionLane 1 : MCF7 extractLane 2 : K562 extractLane 3 : U937 extractLane 4 : Mouse liver extract

Anti-MPG antibody - ab186854 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MPG antibody (ab186854) at 1/500 dilutionLane 1 : MCF7 cell extractLane 2 : K562 cell extractLane 3 : U937 cell extractLane 4 : Mouse liver extract

Anti-MPG antibody - ab37983 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-MPG antibody (ab37983) at 1 µg/ml + HEK293 lysate (RIPA buffer, 35µg total protein per lane). developed using the ECL technique

Anti-MPG antibody - ab83878 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MPG antibody (ab83878) at 1 µg/ml (in 5% skim milk / PBS buffer) + Jurkat cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-MPG antibody [EPR10959(B)] - ab155092 from Abcam

Prices $398.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10959(B)
All lanes : Anti-MPG antibody [EPR10959(B)] (ab155092) at 1/10000 dilutionLane 1 : HeLa cell lysateLane 2 : 293T cell lysateLane 3 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-MPG Antibody (aa46-315, Biotin) - LS-C297720 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MPG Antibody (C-Terminus) - LS-C102131 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MPG antibody LS-C102131 Western blot of Jurkat lysate.

Anti-MPG Antibody (C-Terminus) - LS-C40493 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MPG antibody LS-C40493 Western blot of Jurkat lysate.

Anti-MPG Antibody (aa286-298) - LS-C55115 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody staining (2 ug/ml) of K562 lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.

Anti-MPG Antibody (aa70-296, Biotin) - LS-C297812 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MPG Antibody (aa46-315) - LS-C295652 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant MPG.

Anti-MPG Antibody (aa32-300) - LS-C295653 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant MPG.

Anti-MPG Antibody (aa32-300, FITC) - LS-C301411 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MPG Antibody (aa46-315, FITC) - LS-C301409 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MPG Antibody (aa70-296) - LS-C295650 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant MPG.

Anti-MPG Antibody (aa32-300, Biotin) - LS-C300569 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MPG Antibody (aa70-296, FITC) - LS-C305211 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MPG Antibody - LS-C311397 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MPG Antibody (aa1-148) - LS-C311522 from LifeSpan Bioscience

Prices $250.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MPG Antibody (aa1-90, Azide-free) - LS-C326830 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
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