| Gene Symbol |
MPG
|
| Entrez Gene |
4350
|
| Alt Symbol |
AAG, ADPG, APNG, CRA36.1, MDG, Mid1, PIG11, PIG16, anpg
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
N-methylpurine-DNA glycosylase
|
| Other Description |
3' end of the Mid1 gene, localized 68 kb upstream the humanzeta globin gene on 16p|3-alkyladenine DNA glycosylase|3-methyladenine DNA glycosidase|CRA36.1 (3-methyl-adenine DNA glycosylase)|DNA-3-methyladenine glycosylase|N-methylpurine-DNA glycosylase, MPG|proliferation-inducing protein 11|proliferation-inducing protein 16
|
| Swissprots |
G5E9E2 Q9NNX5 Q15961 Q96S33 Q15275 Q96BZ6 P29372 Q13770 Q5J9I4
|
| Accessions |
AAB58462 AAK61213 AAM14628 ABD95906 CAA93540 CAI95610 CAM26663 EAW85870 EAW85871 EAW85872 P29372 AK308654 AL520052 AW083039 AY258284 AAP82229 BC014991 AAH14991 BG823448 BM796301 DQ895912 ABM86838 L10752 AAF77073 M71215 AAA58369 M74905 AAA58627 M99626 AAB46421 S51033 AAB19537 X56528 CAA39875 NM_001015052 NP_001015052 NM_001015054 NP_001015054 NM_002434 NP_002425
|
| Function |
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:23290262}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000269|PubMed:23290262}. Nucleus {ECO:0000269|PubMed:23290262}.
|
| Top Pathways |
Base excision repair
|