ACOT7

Gene Symbol ACOT7
Entrez Gene 11332
Alt Symbol ACH1, ACT, BACH, CTE-II, LACH, LACH1, hBACH
Species Human
Gene Type protein-coding
Description acyl-CoA thioesterase 7
Other Description CTE-IIa|acyl-CoA thioesterase 2|acyl-CoA thioesterase, long chain|brain acyl CoA hydrolase|brain acyl-CoA hydrolase|cytosolic acyl coenzyme A thioester hydrolase|long chain acyl-CoA thioester hydrolase
Swissprots B3KQ12 A8K0K7 A8K232 Q9Y539 Q53Y78 Q5JYL5 O43703 Q9UJM9 A8K6B8 A8K837 Q5JYL4 Q5JYL6 Q5JYL2 Q9Y540 Q5JYL3 O00154 Q5TGR4
Accessions EAW71527 EAW71528 EAW71529 EAW71530 EAW71531 EAW71532 O00154 AB074415 BAC20174 AB074416 BAC20175 AB074417 BAC20176 AB074418 BAC20177 AB074419 BAC20178 AK057168 BAG51874 AK289572 BAF82261 AK290097 BAF82786 AK291583 BAF84272 AK292202 BAF84891 AK300831 BAG62482 AK304465 BAH14193 AL702662 BC017365 AAH17365 BG332214 BM807217 BQ067921 BT006888 AAP35534 BU594651 D88894 BAA24350 U91316 AAB61211 NM_007274 NP_009205 NM_181864 NP_863654 NM_181865 NP_863655 NM_181866 NP_863656 NM_181862 NM_181863
Function Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May play an important physiological function in brain. May play a regulatory role by modulating the cellular levels of fatty acyl- CoA ligands for certain transcription factors as well as the substrates for fatty acid metabolizing enzymes, contributing to lipid homeostasis. Has broad specificity, active towards fatty acyl-CoAs with chain-lengths of C8-C18. Has a maximal activity toward palmitoyl-CoA.
Subcellular Location Isoform 1: Mitochondrion.
Tissue Specificity Isoform 4 is expressed exclusively in brain. {ECO:0000269|PubMed:12435388}.
Top Pathways Fatty acid elongation, Biosynthesis of unsaturated fatty acids

ACOT7 (B-4) - sc-376692 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ACOT7 (B-4): sc-376692. Western blot analysis of ACOT7 expression in Jurkat (A) and SK-MEL-28 (B) whole cell lysates.

ACOT7 (C-2) - sc-376808 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ACOT7 (C-2): sc-376808. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in tubules.

ACOT7 (H-300) - sc-135339 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ACOT7 (H-300): sc-135339. Western blot analysis of ACOT7 expression in Jurkat (A), SK-MEL-28 (B) and U-251 MG (C) whole cell lysates and mouse brain tissue extract (D).

ACOT7 (P-13) - sc-104028 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ACOT7 (S-15) - sc-104029 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ACOT7 antibody - ab85151 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ACOT7 antibody (ab85151) at 1/500 dilution + human fetal brain lysate

Anti-ACOT7 antibody - ab88433 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-ACOT7 antibody (ab88433) at 1 µg/ml + Recombinant tagged full length Human ACOT7 protein (the immunogen) at 0.1 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

Anti-ACOT7 antibody - ab68560 from Abcam

Prices $359.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-ACOT7 antibody (ab68560) at 1/500 dilutionLane 1 : ACOT7 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-ACOT7 antibody [EPR11317(B)] - ab156576 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11317(B)
All lanes : Anti-ACOT7 antibody [EPR11317(B)] (ab156576) at 1/1000 dilutionLane 1 : fetal brain cell lysateLane 2 : A375 cell lysateLane 3 : 293T cell lysateLane 4 : Jurkat cell lysateLysates/proteins at 10 µg/ml per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-ACOT7 antibody [EPR11318(B)] - ab157472 from Abcam

Host Rabbit
Clonality Monoclonal
Clone EPR11318(B)
All lanes : Anti-ACOT7 antibody [EPR11318(B)] (ab157472) at 1/10000 dilutionLane 1 : Fetal brain lysateLane 2 : 293T cell lysateLane 3 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-ACOT7 / BACH Antibody - LS-C306055 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ACOT7 / BACH Antibody (C-Terminus) - LS-C137130 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ACOT7 / BACH Antibody (C-Terminus) - LS-C345640 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of BACH Antibody with human 293T Whole Cell lysate.

Anti-ACOT7 / BACH Antibody (C-Terminus) - LS-C345594 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of ACOT7 Antibody with human 786-0 Whole Cell lysate.

Anti-ACOT7 / BACH Antibody (clone AT1D5) - LS-C200828 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone AT1D5
Western Blot: The 293T cell lysate (30 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human ACOT7 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Anti-ACOT7 / BACH Antibody (clone 1E7) - LS-C134037 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E7
Immunoperoxidase of monoclonal antibody to ACOT7 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml]

ACOT7 Antibody - NBP1-89279 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ACOT7 Antibody - NBP1-89278 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ACOT7 Antibody [NBP1-89278] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11Lane 2: Human cell line RT-4Lane 3: Human cell line U-251MG sp

ACOT7 Antibody (1E7) - H00011332-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E7
Western Blot: ACOT7 Antibody (1E7) [H00011332-M02] - ACOT7 monoclonal antibody (M02), clone 1E7. Analysis of ACOT7 expression in Jurkat.

ACOT7 Antibody - H00011332-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: ACOT7 Antibody [H00011332-B01P] - Analysis of ACOT7 expression in Jurkat.

ACOT7 Antibody (1D5) - NBP2-22569 from Novus Biologicals

Prices $279.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D5
Western Blot: ACOT7 Antibody (1D5) [NBP2-22569] - The 293T cell lysate (30ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human ACOT7 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Monoclonal Anti-ACOT7, (N-terminal) antibody produced in mouse - SAB1402541 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E7
<B>Immunohistochemistry</B><BR/>Monoclonal Anti-ACOT7, antibody produced in mouse, clone 1E7, purified immunoglobulin: <B>Cat. No. SAB1402541</B>: Antibody concentration: 3 μg/mL using human colon tissue.

Anti-ACOT7 antibody produced in rabbit - HPA025735 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ACOT7: <B>Cat. No. HPA025735</B>: Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells as well as cells in molecular layer.

Anti-ACOT7 antibody produced in rabbit - HPA025762 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ACOT7: <B>Cat. No. HPA025762</B>: Immunohistochemical staining of human soft tissue shows strong cytoplasmic positivity in peripheral nerve cells.

ACOT7 Antibody - C-terminal region (ARP62323_P050) - ARP62323_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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