CACNA1F

Gene Symbol CACNA1F
Entrez Gene 778
Alt Symbol AIED, COD3, COD4, CORDX, CORDX3, CSNB2, CSNB2A, CSNBX2, Cav1.4, Cav1.4alpha1, JM8, JMC8, OA2
Species Human
Gene Type protein-coding
Description calcium channel, voltage-dependent, L type, alpha 1F subunit
Other Description voltage-dependent L-type calcium channel subunit alpha-1F|voltage-gated calcium channel subunit alpha Cav1.4
Swissprots O60840 O43901 A6NI29 F5CIQ9 Q9UHB1 O95226
Accessions AAB92359 CAA06916 EAW50677 EAW50678 EAW50679 EAW50680 EAW50681 EAW50682 EAW50683 O60840 AA019975 AF067227 AAD03587 AF201304 AAF15290 AJ224874 CAA12175 BM931932 JF701915 AED89557 XM_011543983 XP_011542285 NM_001256789 NP_001243718 NM_001256790 NP_001243719 NM_005183 NP_005174
Function Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1F gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin- GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Expression in skeletal muscle and retina. {ECO:0000269|PubMed:10873387}.
Top Pathways Alzheimer's disease, Arrhythmogenic right ventricular cardiomyopathy (ARVC), cAMP signaling pathway, MAPK signaling pathway, Calcium signaling pathway

CACNA1F overexpression lysate - LY417463 from Acris Antibodies

Category Cell Lysate
Prices $480.00
Sizes 100 µg

Cav1.4 Overexpression Lysate (Native) - NBP2-10486 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: Cav1.4 Overexpression Lysate (Adult Normal) [NBP2-10486] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Cav1.4.

Panoply™ Human CACNA1F Knockdown Stable Cell Line - CSC-DC002257 from Creative biogene

Category Cell Line
Species Human
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