ACD

Gene Symbol	ACD
Entrez Gene	65057
Alt Symbol	PIP1, PTOP, TINT1, TPP1
Species	Human
Gene Type	protein-coding
Description	adrenocortical dysplasia homolog (mouse)
Other Description	POT1 and TIN2 organizing protein|POT1 and TIN2-interacting protein|TIN2 interacting protein 1|adrenocortical dysplasia protein homolog
Swissprots	Q9H8F9 Q562H5 Q96AP0
Accessions	AAX82621 EAW83154 EAW83155 Q96AP0 AF070535 AK023726 BAB14658 AK125623 AK301090 BAG62692 AY502940 AAS80318 BC016904 AAH16904 DB040017 XM_005256115 XP_005256172 XR_429727 XR_429728 NM_001082486 NP_001075955 NM_001082487 NP_001075956 NM_022914 NP_075065
Function	Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by increasing telomerase processivity. Plays a role in shelterin complex assembly. May play a role in organogenesis. {ECO:0000269|PubMed:15181449, ECO:0000269|PubMed:16166375, ECO:0000269|PubMed:16880378, ECO:0000269|PubMed:17237768, ECO:0000269|PubMed:20231318}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:15181449}. Chromosome, telomere {ECO:0000269|PubMed:15181449}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PTOP full length protein - ab132458 from Abcam Category Protein Source Wheat germ Species Human

Human PTOP protein fragment - ab126021 from Abcam Category Protein Source E. coli Species Human

ACD / PTOP Antibody Blocking Peptide - LS-E13195 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACD / PTOP Antibody Blocking Peptide - LS-E21312 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACD / PTOP Antibody Blocking Peptide - LS-E21313 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TPP1 / CLN2 Antibody Blocking Peptide - LS-E4681 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TPP1 / CLN2 Antibody Blocking Peptide - LS-E27147 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Tripeptidyl-Peptidase I/TPP1 Protein - H00001200-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human ACD Protein - H00065057-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Tripeptidyl-Peptidase I/TPP1 Protein - H00001200-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ACD Blocking Peptide - 33R-4573 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ACD Blocking Peptide - 33R-8842 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Acd Blocking Peptide - 33R-7345 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ACD - H00065057-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ACD - H00065057-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ACD fusion protein - Ag22523 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PET28a Species Human

ACD fusion protein - Ag23021 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Adrenocortical dysplasia protein homolog(ACD) - CSB-YP839289HU CSB-EP839289HU CSB-BP839289HU CSB-MP839289HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Adrenocorticotropic hormone receptor (MC2R) - MBS1285385 from MyBioSource Category Protein Prices $2,215.00, $2,215.00, $2,680.00, $2,680.00 Sizes 1 mg (E Coli Derived), 100 µg (Baculovirus Derived), 1 mg (Yeast Derived), 100 µg (Mammalian Cell Derived) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ACD (transcript variant 1) - TP304381 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ACD (transcript variant 2) - TP316277 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Adrenocortical Dysplasia Homolog (ACD) - RPC273Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Adrenocortical Dysplasia Homolog (ACD) - RPC273Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

ACD Recombinant Protein Antigen - NBP2-33839PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Tripeptidyl-Peptidase I/TPP1 Recombinant Protein Antigen - NBP1-85561PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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